Mod 4: BBV, Hep, AIDS and emerging viruses Flashcards
BBV
blood borne viruses HBV HCV HIV
hepatitis
inflammation of liver
symptoms: jaundice, dark pee, light poop
Hep A
not a bbv, but has similar symptoms so must test to determine which virus is causing symptoms
previously called (hep a)
infectious hep (but all viral hepatitis infectious) short incubation hep (but incubation varies for all types)
causative agent (hep a)
HAV- contaminated food or H2O ingested by new host replicates in mouth, intestine and liver via bile duct
HAV infection (hep a)
most hosts get typical hep symptoms usually no permanent liver damage; don’t usually die
diagnosis (hep a)
test blood for anti-HAV antibodies
transmission (hep a)
via food or h2o contaminated with feces or saliva
Hep B
bbv
previously called (hep b)
serum hep have long incubation hep
entry into host (hep b)
blood-replicates in liver- hbv in blood etc
HBV infection
most hosts asymptomatic
chronic carriers (hep b)
5-10 %
transmission (hep b)
via blood
diagnosis (hep b)
test blood for serological markers
Hep C
bbv
transmission (hep c)
via blood
chronic carriers (hep c)
common; high risk of cirrhosis or liver cancer
causative agent
HV enveloped
viral relication of HIV/AIDS
attachment to susceptible host cell fusion to host cell penetration RNA-> DNA incorporation of viral DNA into host cell DNA
Effect of HIV on host cells
kills helper t cells when number is significantly reduced, get clinical symptoms of AIDS