Mod 12 Aging: Theories

Question 1

1. Programmed Aging of the cell

Answer 1

-Apoptosis determines when cellular function will cease
-Genes switch on and off
-Ex: female ovary is programmed to apoptosis at 55 yrs

Question 2

2. Telomere Shortened Theory

Answer 2

-Cells can only go through mitosis limited amount of times

Question 3

3. Damage Based Theory of Aging

Answer 3

-Cellular death related to exposure to toxicities over a long period of time or inability for cellular repair

Question 4

4. Free Radical

Answer 4

-Targets DNA via chemical instability
-Oxidizing agents that cause damage
-Ex: Cigarette smoke contains free radicals and cause damage

Question 5

5. Immunosenescence

Answer 5

-Weakening of the adaptive and innate immune systems
-Older adult = decreased WBC, less sensation of pain, reduced ability to get a fever

Question 6

6. Life Prolonging Calorie Restricted Diets

Answer 6

-Limitng daily calories can extend lifespan