Mod 1 Flashcards
Interventional/experimental studies purpose
Purpose = test hypothesis
Interventional/experimental studies
Manipulate ≥ 1 factor and measure outcomes
Independent and dependent variables
Can determine causal relationships
Interventional/experimental studies limitation
Hard for nutrition because you can’t control all the variables
Epidemiological/observational studies purpose
Purpose = generate hypothesis
Epidemiological/observational studies
Test correlation between exposure and outcome
Can make associations and look at complex relationships
Epidemiological/observational studies limitation
Can’t prove a causal relationship
Cross-sectional
Measure exposures and outcomes simultaneously
Remember: NHANES study
Retrospective
Observe the outcome first and look back to determine the exposure
Compare an individual with a condition to an individual without
Prospective
Look at the exposure first and determine the outcome
Follow a group of people with similar characteristics over a long period of time
Necessary
If the cause is not there → the outcome won’t occur
Prerequisite
Test for Necessary
Prove by removing the factor
Sufficient
If the cause is there → the outcome will occur
Test for Sufficient
Prove by adding the factor in
Contributory
The cause is necessary and/or sufficient only under certain conditions
Issues with assessment of exposures
Lack of reliable measurements
Potential confounding factors and biases
24 Hr Recall
Food and drink recorded over 24 hours
Many not represent usual intake
Recall bias
Issues with assessment of health outcomes
Indexes and biomarkers of disease are used instead of the specific disease
Nutritional assessments are usually not specific to nutrition
Food frequency questionnaire
Food intake patterns
Limited in accuracy and completeness
Have to know target population