Mock 2 Flashcards
What is the initial treatment for DKA if the child who presented to A&E with nausea and vomiting, is clinically dehydrated and is now not alert?
IV fluids (0.9% NaCl 10 ml/kg) + SC insulin (0.2units/kg/hr)
Aside from hyperglycaemia, acidosis and ketonaemia, which other abnormality may be seen on blood investigation of DKA prior to treatment?
Mildly raised creatinine
Why does hyperkalaemia occur in DKA ?
Acidosis and lack of insulin means K+ is not moved into cells
Note once insulin and IV fluids have been given K+ levels will fall and should be monitored to avoid hypos
A 9-year-old, has been experiencing a fever, cough and runny nose for the last few days. However, this morning, his dad said that he noticed a rash that started behind his ears and has spread down over his body. He seems very unsettled, and his fever has been getting progressively higher and is now at 39 degrees. What is the likely diagnosis?
Measles
Clinical features of Turner Syndrome
Hypothyroidism
Congenital heart defects
Short statue
Webbed neck
Widely spaced nipples
Which three vaccines should a baby receive at 8 weeks old?
6 in 1 + rotavirus + MenB
Which vaccines should an infant receive at 12 weeks
6 in 1 (again) rotavirus (again), pneumococcal
Which vaccines should an infant receive at 16 weeks
6 in 1 (again) Men B (again)
Which vaccines should an infant receive at 1 year
Men B (again), pneumococcal (again), HiB, Men C and MMR
First line treatment for oligoarticular JIA
Intra-articular steroid injection
Used as a bridging agent when starting methotrexate
When is methotrexate more effective ?
Polyarthritis (useful)
What should be monitored for a child of methotrexate ?
Liver function
Bone marrow suppression
What is chronic anterior uveitis a complication of ?
Junior idiopathic arthritis
Seen in 33% of cases
Child with JIA are screened every 3 months as hard to pick up
What drugs can cause Stephen-Johnson syndrome?
Allopurinol
Lamotrigine
Penicillin
Phenytoin
What is Stephen-Johnson syndrome ?
A rare condition arising from ‘over-reaction’ of the immune system to a trigger such as a mild infection or a medicine, leading to blistering and peeling of the skin and surfaces of the eyes, mouth and throat.
Associated with a red/purple target like rash that spread and forms blisters
The mucous membranes of the mouth may also become blistered and ulcerated
At what age will a baby raise its head to 45 degrees from horizontal, follow moving objects by turning their head and smile responsively?
6 weeks
A 13-year-old male presents to his GP along with his mother. His mother describes her son appearing distant at times and falling behind at school, despite being very bright. She reports his attention as being generally poor. She describes him being clumsy in the morning and often dropping his breakfast. She noticed him jerking this morning and decided to get it checked out. What is the most likely diagnosis?
Juvenile Myoclonic epilepsy
Typical age of onset for juvenile myoclonic epilepsy ?
10–20 years
Typical features of juvenile myoclonic epilepsy
Myoclonic jerks up to 2 hours after waking up
Period of absence which disrupt school but learning is normal
You assess an 8-year-old boy in your paediatrics clinic who was referred by his GP. The referring letter states his mother has described a classic presentation of seizures, having had 3 to date. There is also a family history of epilepsy. You take a history and perform a thorough neurological examination, which is all normal. You agree that he is likely to be having seizures. What is the most appropriate first step?
Request an EEG and follow up when results are back
Complications of chickenpox
Bacterial superinfection
Cerebellitis
Disseminated intravascular coagulation
Progressive disseminated disease
How would the CSF appear in bacterial meningitis
Turbid appearance, raised polymorphs, raised protein and low glucose
How would the CSF appear in viral meningitis
Clear appearance, raised lymphocytes, raised or normal protein, normal/low glucose
How would the CSF appear in encephalitis
Clear appearance, normal/raised lymphocytes, normal/raised protein, normal/low glucose
How would the CSF appear in TB meningitis
Turbid/clear appearance, raised lymphocytes, raised protein, low glucose
What is the causative organism in scarlet fever ?
Group A streptococcus (strep pyogenes)
A 6-year-old male presents after having blood in his urine for 3 days. A urine dip is performed. On examination, there is a palpable mass on his left side. What is the most important diagnosis to exclude?
Wilms tumour
Between what ages does a Wilms tumour usually present ?
5-10 years
What is the classic presentation of a Wilms tumour ?
Abdominal mass
Painless haematuria
What is a Wilms tumour ?
Most common type of kidney cancer in children
Also known as nephroblastoma
A 10-year-old male is seen by his GP. He has severe learning difficulties and global developmental delay. He has characteristic facies of a large head, long face, large everted ears, and a prominent mandible. He also has mitral valve prolapse and poor muscle tone. What is the most likely underlying genetic syndrome?
Fragile X syndrome
Classical presentation of Downs syndrome
Learning difficulty,
Decreased muscle tone
Face-small chin, epicanthic folds, poor
Muscle tone, flat nasal bridge, single palmar crease, protruding tongue.
A 16-year-old male is seen by his GP. He has delayed onset of puberty-small penis, reduced testicle size and no facial or body hair. He also had a reduced sense of smell, poor balance and learning difficulties. What is the most likely underlying diagnosis?
Kallmann syndrome
How could Turner’s syndrome present ?
Female
45XO
Premature ovarian failure
Delayed/absent puberty
Short stature
Learning disability
Congenital heart defects - coarctation of the aorta
Horseshoe kidney
A 2-year-old female presents with multiple itchy lesions mainly on the face and trunk, with some on the limbs. The lesions appeared 3 days ago and are papular with surrounding erythema. Some lesions have been scratched, bled and scabbed over. She has had a mild fever but is largely well. What is the most likely diagnosis?
Chickenpox
Small pustules that develop a honey-coloured crusted plaques usually on the face with no surrounding erythema, often not itchy
Impetigo
A neonate presents with poor feeding, irritability, and fever. They have a purpuric rash appearing. On examination, they have a bulging fontanelle. A lumbar puncture is performed and is found to have raised polymorphs, high protein and low glucose. Given the diagnosis, what is the most likely causative organism
Group B streptococcus
(Could also be E.coli or listeria monocytogenes)
What are RFs for completed suicide ?
Male
Violent method
Care taken to not be found
Leaving a note
Carrying out final acts
First rank symptoms of schizophrenia
3rd person auditory hallucinations
Delusional perceptions
Somatic passivity
Thought alienation
What is somatic passivity ?
The belief that external forces control your actions, thoughts and perceptions
What drug can be used to treat the extrapyramidal side effects of APs ?
Procyclidine
Extra-pyramidal side effects of APs ?
Tardive dyskinesia
Akathisia
Parkinsomia
Dystonia
Features of a hypomanic episode
Flight of ideas
Irritability
Reduced need for sleep
Sexual disinhibition
What is knight’s move thinking ?
When a patient’s thoughts move from one topic to another without any logical connection between them
A feature common in schizophrenia
What differentiates knights move thinking and flight of ideas ?
There is at least some vague connection between subjects in flight of ideas
What blood cell change is associated with lithium ?
Leukocytosis (increased leucocytes)
How often should thyroid and renal function be tested in patients taking lithium ?
Every 6 months
Once therapeutic dose is reached how often should lithium levels be tested ?
Every 3 months
How long should SSRI and exposure and response prevention CBT last for before switching the SSRI for a different SSRI when treating OCD ?
12 weeks
2nd line medication treatment for OCD
TCA - clomipramine
A 17-year-old boy is brought in by his mother, who is concerned about her son. She says, over the last 9 months his performance at school has deteriorated. He’s told his mother on more than one occasion that his headteacher has put a thought in his head that he should drop out of school. He occasionally hears the sound of a bell that he cannot locate the source of. On questioning, he tells you his headteacher is able to control his actions, making him sit in a chair all day and not talk to anyone. He said this was done through a controlling machine in his office, transmitting signals through the bell tower. What best describes this phenomenon?
Delusion of passivity
What is a delusion of passivity ?
When someone experiences their own feelings/impulses/thoughts/actions not as their own but as being imposed on by some external force
What type of hallucination is the feeling of buys crawling under your skin
Tactile hallucinations which are a type of somatic hallucinations
What is thought broadcast?
The fixed idea that other people can read your thoughts
What are the components of a capacity assessment
Ability to understand
Ability to retain
Ability to weigh up
Ability to communicate
What are egodystonic thoughts ?
Thoughts that are very different from a patient’s normal beliefs and values
Common in COD
What are egosyntonic
Thoughts that are similar to a patient’s normal beliefs and values
What is test could be used in primary care to test cognitive function ?
6CIT
The 6 item cognitive impairment test
What is the 6CIT
A brief cognitive function test which takes less than 5 mins and is widely used in primary care settings
What medications are associated with delirium ?
Furosemide
Oxybutynin
Propranolol
Ranitidine