Mobility Pharmacology Flashcards

1
Q

RA Medication Classifications

A

NSAIDS
Corticosteroids
DMARDs

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2
Q

DMARDs Classifications

A

Methotrexate
Sulfasalazine
Biologic DMARDs

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3
Q

Methods used

A

RA treatment:
Rapid anti-inflammatory effects
Bone marrow suppression and hepatotoxicity
Jbianand knitting Frequent lab monitoring of CBC and chem panels bs

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4
Q

Sulfasalazine

A

RA treatment:

Milder effects and safer

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5
Q

Biologic DMARDs

A

RA Treatment:
Aimed at interrupting the progression of the disease
Entanercept (Enbrel)
↑ risk of infection

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6
Q

4 main classifications to treat osteoporosis

A

SERMs
Biphosphonates
Calcitonin
Calcium supplements

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7
Q

SERMs

A

Osteoporosis treatment:

Mimic estrogen by ↓
bone absorption w/o stimulating tissues of breast or uterus

Raloxophene (Evista)

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8
Q

SE of SERMs

A

Osteoporosis treatment:

Leg cramps
Hot flashes
Blood clots

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9
Q

Biphosphonates

A

Osteoporosis treatment:

Alendronate (Fosamax) 1x/week
Ibandronate (Boniva) 1x/month

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10
Q

SE of biphosphonates

A

Osteoporosis treatment:

Weight loss
anorexia
gastritis

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11
Q

Calcitonin

A

Osteoporosis treatment:

Inhibits bone resorption and is secreted by the thyroid gland.

Salmon calcitonin (Calcimar)

Can’t be orally absorbed. Stopped at some point in GI

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12
Q

OA Medication Classifications

A

Salicylates
Topical analgesics like capsaicin cream (Zostrix)
NSAIDs

Steroids are a second step
Depo-Medrol

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13
Q

Goal of treatment of Myasthenia Gravis

A

Increase amount of acetylcholine for muscle contraction

Decrease muscle weakness, fatigue

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14
Q

Chronic Gout Medications

A
Xanthine oxidase inhibitor (Allupurinol)
Uricosuric probenecid 
Febuxostat
Corticosteroids
ACTH
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15
Q

Acute Gout Medications

A

Colchine
NSAIDs
corticosteroids

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16
Q

SE of Colchicine

A
muscle pain / weakness
numbness/tingly in fingers or toes
Severe vomiting
Diarrhea
fever
chills
body aches
flu symptoms
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17
Q

Drug therapy for lupus

A
NSAIDs
Antimalarials
Corticosteroids
Immunosuppressives
Immunomodulators
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18
Q

Alpha 1

A

Smooth muscle contraction

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19
Q

Beta 1

A

↑ HR

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20
Q

Beta 2

A

bronchodilation

21
Q

Beta 3

A

Site of lipolysis

22
Q

Use spacers with

A

MDIs

23
Q

2 categories of respiratory medications

A

BAM

SLM

24
Q

BAM

A

bronchodilators

beta 2 agonists “-terol”
Anticholinergic agents “-pium”
Methylxanthines “-phylline”

25
Q

SLM

A

Anti-inflammatory agents

Steroids “-sone”
Leukotrienes “-lukast”
Mast Cell Stabilizers “-crom”

26
Q

Beta 2 agonist medications

A

Albuterol
Solumedrol

You’ll see ↑ HR and bronchodilation

27
Q

Anticholinergic Agent medicaitons

A

Ipratropium

Bring ↓ mucus prod. in bronchi and bronchioles

28
Q

Methylxanthines

A

Theophylline

Causes sympathetic response
↑ HR, opens the lungs

29
Q

Steroids/Corticosteroids Medications

A

Prednisone
Methylprednisone
Prednisolone

Causes sympathetic response
↑ HR and opens lungs

Must wean off these

30
Q

Leukotrienes

A

Singulair, Montelukast
“Luke likes to sing”

Cause bronchi and bronchioles to relax

31
Q

Mast cell stabilizer medications

A

Cromolyn
“mass of chrome”

Reduce swelling and inflammation

32
Q

Bronchodilator adverse effects

A
tachycardia and palpitations
headache
tremor
restlessness
nervousness

Toxicity r/t theophyline

33
Q

Adverse effects of inhaled corticosteroids

A
candidiasis of mouth/throat
hoarseness
slow growth in children
adrenal suppression long-term
↑ risk of cataracts
34
Q

Adverse effects of leukotriene receptor antagonists

A

restlessness
headache
upper resp. tract infection

35
Q

Which works quickly to relax smooth bronchial muscle resulting in widened airway?
First in line for acute attack

A

Albuterol

36
Q

Antihistamines act on which receptor

A

H1 receptor agonist

Inhibits smooth muscle constriction in BV, respiratory, and GI tracts

Decrease capillary permeability

37
Q

What are antitussives

A

Drugs that suppress cough

38
Q

What are expectorants?

A

render the cough more productive by stimulating the flow of resp. tract secretions

39
Q

Mucolytics

A

react directly with mucus to make it more watery. This makes cough more productive

Acetylcysteine

40
Q

Nasal Decongestants

A

Stimulate alpha1-adrenergic receptors on nasal BV

Causes vasoconstriction causing shrinkage of swollen membranes

41
Q

Intranasal Corticosteroids

A

Have inflammatory actions

Prevent or suppress all major symptoms of allergic rhinitis

42
Q

Intranasal Corticosteroids Medications

A

fluticasone (Flonase)

mometasone (Nasonex)

43
Q

Intranasal corticosteroids suffix

A

“-sone”

44
Q

What is the medication central to symptom management for COPD?

A

bronchodilator medications

Inhaled therapy preferred

45
Q

What are more effective, short or long acting bronchodilators?

A

Long-acting inhaled bronchodilators

46
Q

Side effect of Rifampin (TB medication)

A

Orange colored body secretions

47
Q

TB medication

A

Rifampin

48
Q

steroid suffix

A

“-sone”