MNT for Short Bowel Syndrome Flashcards

1
Q

____ ____ ____ is explained as the metabolic and nutritional consequences which result from inadequate bowel mucosal absorptive surface area

A

Short bowel syndrome

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2
Q

Having inadequate bowel mucosal absorptive surface area means that someone is unable to support their ____ and ____ requirements

A

Nutritional and fluid

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3
Q

Short Bowel Syndrome is caused by a deficiency in bowel length due to extensive ____ resection

A

Surgical

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4
Q

Short bowel syndrome is characterized by…

A

-Severe, chronic diarrhea and steatorrhea
-Malabsorption of macro- and micro-nutrients
-Dehydration
-Electrolyte imbalances
-Progressive weight loss and malnutrition

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5
Q

Diarrhea with small bowel syndrome is due to…

A

-Malabsorption
-Altered motility
-Increased secretion

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6
Q

It is difficult to diagnose small bowel syndrome on ____ alone; we need to consider symptoms as well

A

Length

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7
Q

Diagnosing short bowel syndrome on length has what requirements?

A

-Loss of 70-75% of small bowel
-<200 cm of remaining small bowel length

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8
Q

If someone has >75% of bowel removed or less than 100 cm remaining, they will have severe malabsorption and will likely need ___ ____ for survival

A

Parenteral nutrition

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9
Q

Etiology of small bowel syndrome in adults:

A

-Crohn’s disease
-Mesenteric infarct
-Small bowel volvulus
-Radiation enteritis
-Cancer

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10
Q

Etiology of small bowel syndrome in children:

A

-Necrotizing enterocolitis
-Small bowel volvulus
-Intestinal atresia
-Crohn’s disease

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11
Q

What factors influence the severity of small bowel syndrome?

A

-Remaining bowel length and condition of the remaining bowel
-Location of resection
-Presence of the ileocecal valve
-Presence of the colon
-Degree of adaptation of the remaining bowel

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12
Q

____ increases with increased amount of small bowel removed or non-functional

A

Malabsorption

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13
Q

The minimal small intestine length necessary for adequate absorption of oral/enteral nutrition is…

A

-100 cm of small bowel if no colon
-60 cm of small bowel with an intact colon

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14
Q

We need to consider nutrients absorbed and the functions of the segments of intestine _____

A

Removed

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15
Q

If someone has a duodenal resection, ___ ___ may occur

A

Dumping syndrome

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16
Q

If someone has a jejunal resection, they may experience ___ intolerance

A

Lactose

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17
Q

Someone may have adequate absorption unless >___% of their jejunum has been removed

A

75

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18
Q

The ____ can assume the absorptive functions of the jejunum

A

Ileum

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19
Q

The ileum is the only site for absorption of what two things?

A

-Bile salt
-Vitamin B12

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20
Q

A resection of > 100 cm of the ileum results in a net loss of bile salts, leading to ____ and ____ ____

A

-Steatorrhea
-Cholerrheic diarrhea

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21
Q

Large resections of the ileum can result in severe malabsorption of…

A

-Fat
-Fat-soluble vitamins
-Calcium
-Magnesium
-Zinc
-Selenium
-B12

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22
Q

Ileal resections can result in loss of the ___ ___

A

Ileal break

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23
Q

End-jejunostomies can result in…

A

-Dehydration
-Electrolyte deficiencies

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24
Q

Loss of the ileocecal valve can result in ____ ____

A

Bacterial overgrowth

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25
With a partial or total colon resection, there is an increased risk of ____ and ___ ___
-Dehydration -Electrolyte losses
26
Intestinal transit time will be ____ with the presence of a colon
Prolonged
27
The ___ ___ slows gastric emptying
Colonic break
28
Having an intact colon means that you can metabolize ____ ___ ___ ___, which provides a source of calories
Short-chain fatty acids
29
Whatever small bowel is remaining undergoes structural and functional changes to increase ____ ____
Nutrient absorption
30
What types of changes occur in the remaining small bowel?
-Hyperplasia -Elongation -Increase height of the villi -Increases in brush border enzymes
31
Intestinal adaptation occurs over ___-__ years after surgery
1-2
32
What factors influence adaptation?
-Oral/enteral nutrition -Complex luminal nutrients vs simple -Glutamine -Short-chain fatty acids -Hormones (enteroglucagon, glucagon-like peptide 1, peptide YY, growth hormone)
33
Those with small bowel syndrome have an increased rate of gastric emptying due to...
-Loss of intestinal hormones and feedback control -Loss of the pyloric sphincter
34
If someone has an ileal resection, they would have ____ transit in remaining bowel
Rapid
35
Someone with short bowel syndrome would have impaired absorption of...
-Fluid and electrolytes -Bile salts->cholerrheic diarrhea -Fat->steatorrhea -Fat-soluble vitamins -Vitamin B12 -Minerals: Zinc, calcium, magnesium, manganese, copper, selenium, and chromium -Lactose
36
Gastric _____ can occur after significant small bowel resections
Hypersecretion
37
A decrease in ____ and ____ secretion leads to increased serum gastrin levels and increased gastric acid secretion
Cholecystokinin and secretin
38
What are the clinical manifestations of having increased gastric acid secretion?
-Increases volume of secretions entering the small bowel and promotes diarrhea -Acid damage to the intestinal mucosa -Denatures pancreatic enzymes -Precipitates bile salts - disrupts micelle formation -Stimulates peristalsis
39
Small bowel bacterial overgrowth is caused by...
-Removal of the ileocecal valve -Blind loops -Antimotility medications -Acid-suppression medications
40
Small bowel bacterial overgrowth results in...
-Deconjugated bile salts -Inflammatory mucosal damage -Gas -Abdominal bloating and pain -Steatorrhea -Fat-soluble vitamin and B12 deficiencies
41
With steatorrhea, ____ is preferentially bound to unabsorbed fatty acids instead of _____
Calcium; oxalate
42
Increased absorption of free oxalate leads to ____
Nephrolithiasis
43
Hyperoxaluria and nephrolithiasis occur only if the _____ is present
Colon
44
The risk of hyperoxaluria is increased with ____ ____
Volume depletion
45
Vitamin B12 or folate deficiency can lead to _____ _____
Macrocytic anemia
46
People with short bowel syndrome may develop metabolic bone disease due to...
-Malabsorption of vitamin D and calcium -Metabolic acidosis
47
What should be included in a nutrition assessment for someone with short bowel syndrome?
-Thorough knowledge of current medical status -Current GI symptoms/complications -Remaining small bowel anatomy -Weight history -Diet history: analysis of home diet/nutrition support, supplement use -NFPE -Input/output records -Lab assessment: electrolytes, malabsorption workup, vitamin and mineral levels -Food-medication interactions
48
Energy requirements for someone with short bowel syndrome should be ____
Individualized
49
On overage, people with short bowel syndrome should get ___-____ kcal/kg, but some people may need up to ___ kcal/kg
35-45; 60
50
For people with short bowel syndrome on parenteral nutrition, they should receive ____ kcal/kg
32
51
Someone with short bowel syndrome who eats orally or is on enteral nutrition should get ___-___ g/kg of protein per day
1.5-2
52
For someone with short bowel syndrome on parenteral nutrition, they should receive ___-___ g/kg of protein
1.0-1.5
53
What things might increase protein needs for someone with short bowel syndrome?
-Malnutrition -Recent surgery -Presence of other diseases or conditions -Malabsorption
54
Those with short bowel syndrome have ____ fluid needs due to diarrhea/ostomy output
Increased
55
For ostomy patients, oral consumption of fluid should be ____ than ostomy output
Greater
56
We should monitor fluid intake/output closely and ____ losses
Replace
57
___ ___ ____ should be sipped slowly throughout the day
Oral rehydration solution
58
If someone has over ___ ____ of ostomy output per day, they should receive IV fluids with electrolytes
2 liters
59
Phase I of post-operative short bowel syndrome lasts the initial ___-___ weeks post surgery
1-3
60
What may happen during phase 1 of post-operative short bowel syndrome?
-Severe malabsorption -Hypersecretion of gastric secretions -Massive diarrhea/ostomy output -Rigorous IV repletion of fluid and electrolyte losses
61
Someone in phase I post-op short bowel syndrome should be ____ and receive ____ for nutrition support
NPO, TPN
62
Phase II post-op short bowel syndrome lasts ___-___ months
1-3
63
During phase II, ____ malabsorption occurs with deficiencies in fat-soluble vitamins, calcium, magnesium, and zinc
Fat
64
Phase II is the period of greatest intestinal _____
Adaptation
65
Someone in phase II post of short bowel syndrome should be on _____, with the initiation of enteral nutrition when/if diarrhea or ostomy output decreases to less than 2 liters per day
TPN
66
Phase III post op short bowel syndrome lasts ___-___ months or longer
3-12
67
The goal during phase III is adaptation and transition to ____ diet
Oral
68
In phase III post-op, ____ should be well-controlled
Diarrhea
69
In phase III of the post-op diet, patients should discontinue TPN and increase to full ____/____ feedings
Enteral/oral
70
Not all patients attain phase III of the post-op short bowel syndrome diet; some may be on home ____
TPN
71
Enteral nutrition fosters intestinal ____
Adaptation
72
Usually, enteral nutrition can be implemented within ____ ____ after surgery
1 month
73
Enteral nutrition should be infused into the most ____ area (i.e., stomach) to maximize the absorptive surface area
Proximal
74
Those with short bowel syndrome who are getting enteral nutrition should get ____ infusion
Continuous
75
Patients may need home tube feedings if unable to meet needs with ____ diet alone
Oral
76
Research supports using ____, ____ tube feeding formulas due to increased stimulation of intestinal adaptation and decreased osmotic load
Isotonic, polymeric
77
If the colon is intact, we should use a ____ ____ containing formula (short-chain fatty acids)
Soluble fiber
78
If tube feeding is unsuccessful, try a ____-____/____-____ formula with MCT
Semi-elemental/peptide-based
79
_____ formulas are no longer recommended for those with short bowel syndrome
Elemental
80
When determining macronutrient distribution, we need to consider ____
Anatomy
81
If the colon is in continuity, we should recommend a higher ___, lower ____ diet
Carbohydrate, fat
82
What is the macronutrient distribution we should recommend to a patient with small bowel syndrome who has their colon in continuity?
-50-60% kcal from carbohydrates -20-30% kcal from fat -20% kcal from protein
83
If someone does not have a colon, we should recommend a diet that is ____ is carbohydrates and fat
Moderate
84
What is the macronutrient distribution we should recommend to a patient with small bowel syndrome who does not have a colon?
-40-50% of kcal from carbohydrates -30-40% kcal from fat -20% kcal from protein
85
For anyone with small bowel syndrome, we should promote ____ carbohydrates and ____ fiber (SCFA)
Complex; soluble
86
What are some recommendations for those with short bowel syndrome on oral nutrition?
-Avoid concentrated sweets -5-6 small meals -Chew food thoroughly -Emphasize complex carbohydrates -Limit fluids with meals (sip fluids between meals) -Drink isotonic beverages (oral rehydration supplements( -Liberal use of salt (if no colon) -Avoid caffeine and alcohol
87
We should ____ restrictions for those on oral nutrition
Limit
88
If someone has an intact colon, we should restrict ____ intake
Oxalate
89
What are sources of oxalates?
-Berries -Nuts -Chocolate -Green beans -Celery -Spinach -Beets -Beer -Sweet potatoes -Soy
90
We can recommend a low ____ diet if needed
Lactose
91
We should also provide diet education with sample ____
Menus
92
Those on oral or enteral nutrition should receive a ____ with minerals
Multivitamin
93
We should assess those on oral or enteral nutrition individually for additional _____ of vitamins and minerals
Supplementation
94
If those on oral or enteral nutrition are having steatorrhea, we should provide them with fat-soluble vitamin supplements in a ____-____ form
Water-soluble
95
In the absence of the ileum/large resection, someone on oral or enteral nutrition should receive _____ mcg of vitamin B12 IM injection monthly
1000
96
For someone on oral or enteral nutrition, they should receive a calcium citrate supplementation of ____-____ mg, 1-2 tablets three times per day
500-600
97
For someone on oral or enteral nutrition, they should receive magnesium lactate in ____ mg 1-2 tablets three times per day OR magnesium gluconate ____ mg tablet or liquid, 1-3 tablets three times per day
84; 1000
98
People lose ____ mg of zinc per liter of output
12
99
We should provide ____ mg of zinc sulfate, 1-3 tablets daily
220
100
What would be replenished by oral rehydration supplements?
-Potassium -Sodium -Chloride -Bicarbonate
101
What are examples of pharmacologic management of short bowel syndrome?
-Antimotility/antidiarrheals (ex: loperamide) -Proton pump inhibits and H2-receptor antagonists -Bile acid binders (cholestyramine) -Octreotide (somatostatin analogue)
102
What are food-drug interactions with bile acid binders like cholestyramine?
-Decreased absorption of fat-soluble vitamins, calcium, iron, zinc, magnesium, and folate
103
What can Octerotide (somatostatin analogue) help with?
-Antisecretory action -Antimotility -Reduces stomal output and diarrhea
104
What are food-drug interactions with Octerotide (somatostatin analogue)?
-N/V -Hyperglycemia
105
The FDA has approved trophic factors for management of short bowel syndrome because they enhance intestinal ___ and ____
Adaptation and absorption
106
What are two examples of trophic factors that may be prescribed for the management of short bowel syndrome?
-Growth hormone (Ex: somatotropin) -Glucagon-like peptide 2 analogue (Ex: teduglutide)
107
What are three examples of surgical management of short bowel syndrome?
-Longitudinal intestinal lengthening and tapering -Serial transverse enteroplasy -Small bowel transplantation