Critical Care Nutrition (part 3) Flashcards
Cause of acute kidney injury in the ICU:
Acute tubular necrosis
What are risk factors for acute tubular necrosis:
-Decreased renal perfusion
-Nephrotoxic medications
-Sepsis or systemic inflammatory response syndrome
Treatment options for acute tubular necrosis:
-No dialysis
-Intermittent hemodialysis
-Continuous renal replacement therapy (CRRT)
One example of continuous renal replacement therapy is ____ ____ ____
Continuous venovenous hemodialysis
Continuous venovenous hemodialysis removed ___, ___, and ____ products
Water, electrolytes, and waste
Protein loss is an issue with continuous venovenous hemodialysis; people lose about ___-___ g of protein per day
10-15
People can also absorb ___-___% of dextrose from dialysate
35-45%
Energy needs for someone with acute kidney injury:
25-30 kcal/kg
Protein needs for someone with acute kidney injury who is not on dialysis:
1.2-2 g/kg
Protein needs for someone with acute kidney injury who is having frequent intermittent hemodialysis:
1.0-1.5 g/kg
Protein needs for someone with acute kidney injury who is on continuous venovenous hemodialysis:
1.5-2.5 g/kg
For non-obese patients, we should use ____/____ to calculate kcal and protein needs
UBW/EDW
For critically ill patients with obesity, we should use ____ to calculate kcal and protein needs
IBW
Fluid needs for someone with acute kidney injury in critical illness:
Replace output + 500 mL
Fluid ____ is not usually necessary on continuous renal replacement therapy
Restriction
____ and ____ are usually well-cleared with continuous venovenous hemodialysis, so an electrolyte restriction is not necessary
Potassium and phosphate
Electrolytes (potassium and phosphate) may need to be restricted with ____
Hemodialysis
If someone with acute kidney injury is on enteral nutrition, use a ___-___ enteral formula that meets ICU recommendations for protein and kcal
Non-renal
If someone with acute kidney injury has significant electrolyte abnormalities, consider a ____ ____ enteral nutrition formula
Renal failure
Systemic inflammatory response syndrome causes widespread inflammation resulting from…
-Infection
-Severe acute pancreatitis
-Ischemia
-Burns
-Major trauma
-Hemorrhagic shock
Systemic inflammatory response syndrome causes the release of…
-Cytokines
-Proteolytic enzymes
-Toxic oxygen species
Cytokines increase ____ ____
Capillary permeability
____ and ____ can occur with systemic inflammatory response syndrome, which can lead to organ damage and multi-organ dysfunction syndrome
Hypotension and hypoperfusion
What are two hypotheses for the development of systemic inflammatory response syndrome?
-Excessive production of pro-inflammatory cytokines
-Disruption of gut barrier function, leading to bacterial translocation
Primary multiple organ dysfunction syndrome is caused by direct ___ ___
Organ injury
Secondary multiple organ dysfunction syndrome is caused by ____/____ in other organs (SIRS)
Inflammation/infection
Multiple organ dysfunction syndrome causes failure what organs?
-Lungs
-Kidney
-Liver
-Intestines
MNT for systemic inflammatory response and multiple organ dysfunction syndrome:
-Increased kcal and protein to meet increased metabolic demands (however, avoid overfeeding and use indirect calorimetry if possible)
-Early enteral nutrition (unless hemodynamically unstable)
-If prolonged small bowel ileus, initiate parenteral nutrition
____ is another name for hemodynamic instability
Shock
Shock is treated with high doses of…
-Epinephrine
-Norepinephrine
-Dopamine
-Dobutamine
If someone is in shock, we should withhold ____ ____
Enteral nutrition
Hyperglycemia in the ICU is a large concern; we should promote blood glucose control between ____-____ mg/dL
140-180
In order to help avoid hyperglycemia, we should avoid ____
Overfeeding