MKSAP Rheum

Question 1

In systemic sclerosis, pulmonary arterial hypertension is typically associated with a DLCO less than ___% of predicted and is disproportionately low compared with the decrease in ______ (FVC/DLCO ratio >1.6)

Answer 1

DLCO <60%

lung volumes (FVC/DLCO ratio >1.6)

Question 2

middle aged female with
- enlarged parotid and lacrimal glands
- Multiple coin-sized pink, red, and violaceous papular skin lesion
- digits are swollen and tender.
- Hepatomegaly

disease?
dx test?

Answer 2

Sarcoidosis

skin bx (or affected tissue)

Question 3

___________ is a systemic inflammatory syndrome characterized by fever, abdominal pain, rash, and arthritis, each lasting only several days

Answer 3

Familial Mediterranean fever

Question 4

first line treatment for familial mediterranean fever

Answer 4

daily colchicine

• prevents attacks
• prevents renal amyloidosis
• inhibit neutrophils and suppress interleukin-1β generation