MKSAP Endocrine Flashcards
1
Q
what is hypophysitis?
A
inflammation of the pituitary gland
path: immune checkpoint inhibitors (anti-CTL4 ab, anti-PD-1 ab)
pt: headache/fatigue
2
Q
What DM medications cause weight loss?
A
- glucagon-like peptide-1 (GLP-1) receptor agonists (liraglutide, exenatide, lixisenatide, dulaglutide, semaglutide)
- sodium-glucose cotransporter-2 (SGLT-2) inhibitors (canagliflozin, dapagliflozin, empagliflozin, ertugliflozin)
- amylin mimetics (pramlintide) have been associated with weight loss
3
Q
metformin is weight (positive/negative/neutral)
A
neutral
other weight neutral –> DDP4- inhibitors (-gliptin)
4
Q
teriparatide
MOA?
A
anabolic agent used in osteoporosis
5
Q
In patients receiving anabolic therapy (___________) for osteoporosis, an antiresorptive agent (________) must be started within 1 month of completing the course of anabolic treatment to prevent the loss of newly formed bone.
A
teriparatide, abaloparatide
alendronate (bisphosphonate)
