| MIXED | Flashcards

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1
Q

Describe the exact composition and arrangement of the nucleosome

A

its core particles contain two copies of each histone (H2, 3, 4 and Ha and Hb) and it is 146 bp of super helical DNA wrapped around a histone octomer

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2
Q

Oblong in shape but over time can rapidly change its shape and is small, this defines a chloroplast DNA or a mitochondrial DNA

A

mitochondrial DNA

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3
Q

modification of histone tails via acetylation, methylation, ubiquitination, and phosphorylation, all examples of gene regulation is defined as

A

Chromatin Remodeling

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4
Q

Ribosomes begin translation at the first

A

start codon, AUG

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5
Q

the number of individuals that show at least some degree of expression of a mutated genotype, termed

A

penetrance

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6
Q

DNA entwined around an octet of proteins is called

A

nucleosome

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7
Q

the discipline with in evolutionary biologists that study change in allele frequencies is called this

A

population genetics

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8
Q

term that describes random fluctuation in allele frequenies

A

genetic drift

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9
Q

when a population originates from a smaller number of individuals

A

founder effect

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10
Q

The chi square test involves a statistical comparison between measure (observed) and predicted (expected) values. Degrees of freedom is defined as

A

one less than the number of categories being compared

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11
Q

indicates that the environment has a great influence…

narrow sense score of zero or broad sense score of zero

A

broad sense score of zero!!

0

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12
Q

expression of genes on one homolog, but not the other, is effected is referred to as

A

imprinting

-ie epigenetics

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13
Q

Ribosomal binding sites, | E | P | A |

Translocation happens during…

A

| P | - peptide bond syn and holds the aatRNA carying the next AA to be added to the chain

| A | - codon recognition of new entry

added post are the 5-cap and 3-pony tail

E | - exit, translocation or ribosome moving tRNA from P to E site

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14
Q

How does methylation regulate gene activity…

A

by ALTERING TRANSCRIPTIONAL ACTIVITY by interfering with RNA polymerase during binding

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15
Q

A protein causes the acetylation of histones what effect do you think this will have on a gene in that region…

A

an increase in expression

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16
Q

Type of RNA that introduces no mutations into the organism. it targets mRNA and degrades it….

A

RNAi (interfering)

17
Q

They are necessary for basal low level transcription….

A

They are necessary for basal low level transcription…. Promoter regions

while ENHANCERS are necessary for achiving max lvl transcription

18
Q

mRNA into exons, to product, describes..

A

alternative splicing

19
Q

T or F

represors are cis acting?

A

F

20
Q

a mutation in only one lacoperon gene will directly effect the….

A

repressor (I); the control unit

21
Q

prokaryotic gene expression..

something in the environment induces expression

a. inducible enzymes
b. constitutive enzymes
c. represible expression

A

something in the environment induces expression…inducible enzymes

  • constitutive enzymes - produced continuously regardless of the environment “house cells”
  • represible expression - when expression is stopped, nothing gets made, can be +(only occurs when a regulator molecule directly stimulates RNA production) /-(will occur unless turned off by a regulator molecule)