5| SEX DETERMINATION AND SEX CHROMOSOMES

Question 1

The MSR, male specific region accounts for 95% of the chromosome what two regions does the MSR contain

Answer 1

TDF and SRY

Question 2

A protein encoded by the SRY gene, responsible for male sex initiation is termed

Answer 2

TDF

Question 3

Name four ways to sex in humans can be determined

Answer 3

1. Aneuplodies
2. the Y chromosome is linked to maleness
3. PAR regions (autosomal regions in both sexes)
4. Primordial Germ: Millerian and wolffian (presence/ absence of Y chromosome is key, bi-potential gonads)

;the reproductive system in humans doesn’t occur until fetal development from an undifferentiated zygote

Question 4

Homologous regions shared between the X and Y chromosomes that recombine during meiosis are termed as

Answer 4

Pseudo autosomal regions, PAR

Question 5

Heritable alterations of the X-inactivation center (located on the q arm), can be defined by

Answer 5

Epigenetic inheritance

Question 6

A protein encoded by a gene in the SRY, triggering testies formation

Answer 6

TDF