Mitosis: Division Is Also Multiplication Flashcards

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1
Q

Cell division starts with ______ which has 3 subphases

A

Interphase

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2
Q

3 subphases of interphase

A

G1
S
G2

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3
Q

Next 4 phases of cell division

A

Prophase
Metaphase
Anaphase
Telophase

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4
Q

______ are found in the different stages of cell division that monitor cell division, ensuring its smooth process

A

Checkpoints

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5
Q

G stands for

A

Gap

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6
Q

In ____, the cell synthesizes MRNA and proteins, which are needed for chromosome replication

A

G1

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7
Q

2 checkpoints in G1

A
G1 DNA damage checkpoint
p53 proteins (TP53)
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8
Q

It evaluates the dna’s integrity

A

G1 DNA damage checkpoint

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9
Q

Damaged DNA results in the accumulation of p53 proteins that can trigger either _______ or _______

A

Cell cycle arrest or apoptosis

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10
Q

Are tumor-suppressing proteins that help in regulating the cell cycle

A

p53 proteins (TP53)

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11
Q

Refers to a process of programmed cell death

A

Apoptosis

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12
Q

It evaluates the cell’s capability to undergo cell division

A

Restriction checkpoint

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13
Q

If the cell is ready, it will proceed to S phase, if not, the cell goes to

A

G0

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14
Q

2 cells in G0

A

Quiescent (dormant)

Senescent (aging or deteriorating)

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15
Q

It may go back to cell division with proper stimulus

A

Quiescent cells

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16
Q

One reason cells become senescent is due to

A

damaged DNA

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17
Q

In this phase, chromosomes are replicated which means that there are twice the actual DNA now present in the cell

A

S (synthesis) phase

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18
Q

Each chromosome consists of two _____, which is one copy of a newly copied chromosome

A

Chromatids

19
Q

It monitors the replication process during the S phase

A

S DNA damage checkpoint

20
Q

At this point, the cell rapidly grows and protein synthesis continues

A

G2 Phase

21
Q

It checks activities in G2 to ensure its proper flow

A

G2 DNA damage checkpoint

22
Q

It ensures that DNA synthesis is complete before proceeding to mitosis

A

Unreplicated DNA checkpoint

23
Q

The chromosomes condense and are now visible even with just using the ordinary light microscope

A

Prophase

24
Q

A chromosome consists of two sister chromatids attached to the

A

Single centromere

25
Q

In the late part of prophase, the ______ and the _______ disappear

A

Nuclear envelope and nucleolus

26
Q

A special protein complex appears at the centromere at prophase. Its function is to link the spindle fibers to the centromere

A

Kinetochore

27
Q

3 kinds of microtubles in the spindle fibers

A

Astral microtubules
Polar microtubules
Kinetochore microtubules

28
Q

A kind of microtubules that grow only near the centrosome (the structure with the centrioles)

A

Astral microtubules

29
Q

A kind of microtubules that grow away from the centrosome. These overlap ay the middle where the chromosomes are located, but they are still attached to the kinetochore

A

Polar microtubules

30
Q

A kind of microtubules that are onlu ones attached to the kinetochore

A

Kinetochore microtubules

31
Q

In metaphase, the kinetochore microtubule directs the chromosomes toward the center that is called

A

Metaphase plate or equatorial plate

32
Q

It guarantees the proper alignment of the chromosomes at the metaphase plate and prevents untimely onset of the anaphase

A

Spindle assembly checkpoint

33
Q

Twi substages in anaphase

A

Anaphase A

Anaphase B

34
Q

In anaphase _, the kinetochore microtubules of the spindle fibers separate and move the sister chromatids toward opposite poles

A

A

35
Q

In anaphase _, the polar microtubules begin to elongate, while astral microtubulea pull them on the other side.

A

B

36
Q

Is the process of dividing the cytoplasm into half. It starts at anaphase and continues to the next phase

A

Cytokinesis

37
Q

In _____, the chromosomes uncoil, and both the nucleolus and the nuclear envelope reappear

A

Telophase

38
Q

Cytokinesis, in telophase, continues with the visible appearance of the _____, a groove on the cell membrane between the poles usually observed in animal cells

A

Cleavage furrow

39
Q

In animal cells, the cleavage furrow is produced when the _______, which is made up of proteins, constricts the middle of the cell. This continues until the opposite surfaces of cell membrane are in contact and produces 2 daughter cells

A

Contractile ring

40
Q

It prevents cytokinesis to start until all chromosomes are correctly separated.

A

Chromosome segregation checkpoint

41
Q

The cell wall of plants is a strong substance thus a _________ forms which is involved in forming the cell wall of each daughter cell in plants

A

Cell plate

42
Q

Mitosis ensures that the number of chromosomes of the parent cell is identical to

A

Its 2 daughter cells

46 chromosomes from parent cell
Two 46 chromosomes daughter cells

43
Q

Purposes of mitosis

A
  • ensures that the number of chromosomes of the parent cell is identical to its two daughter cells
  • ensures the growth of the offspring
  • replaces the damaged cells in the wounds
44
Q

Is simply defined as cells that undergo continuous division without stopping

A

Cancer