Mitosis and Meiosis Flashcards

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1
Q

What is chromosomes?

A

Coiled DNA, also contains proteins. It is a gene-carrying structure found during mitosis

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2
Q

What is chromatin?

A

The complex of DNA and proteins that make up chromosomes threadlike in the nucleus during interpahse

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3
Q

What is a chromatid?

A

a single strand of a chromosome which remains joined by a centromere

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4
Q

What are sister chromatids?

A

A chromosome and its duplicate are attached to one another by a centromere until separated during mitosis

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5
Q

What is a centromere?

A

It is the structure that holds chromatids together. It is where the spindle fibres attach to and what holds sister chromatids.

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6
Q

What is a haploid?

A

the number of chromosomes in a gamete. One-half of the full complement of chromosomes, sex cells have haploid chromosome numbers. (n)

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7
Q

What is a diploid?

A

Refers to twice the number of chromosomes in a gamete. Refers to the full complement of chromosomes. Every cell of the body with the exception of sex cells contain diploid chromosome number (somatic) (2n)

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8
Q

What is polyploidy?

A

Having more than 2 (2n) complete copies of the chromosomes.

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9
Q

What is the significance of chromosome number in somatic and sex cells?

A

Sex cells only contain half the amount of chromosomes as the somatic body cells do, they have the complete copy.

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10
Q

Haploid gametes VS diploid cells?

A

Haploid cells are sex cells that only contain 23 chromosomes through meiosis they only contain half of the full complement of chromosomes. While diploid cells are usually body cells and they contain the full complement of 46 chromosomes

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11
Q

What are the events of the cell cycle?

A

The cell cycle contains G1 phase, S phase, G1 phase and finally mitosis/meiosis (nuclear division) phase. Interphase is divided into G1, S and G2 phases, and it contains 90% of the cell’s life cycle.
In the G1 phase, the cell grows to carry out its metabolic processes.
In the S phase the DNA replicates and “births sister chromatids”
The G2 phase is when synthesis is complete.
The main events that occur in interphase are
- the nuclear membrane forms, DNA becomes in the form of chromatin, DNA doubles, and centrioles double.

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12
Q

What occurs in prophase?

A
  • The nuclear membrane dissolves
  • The chromatin thickens and becomes visible separate chromosomes,
  • Centrioles go to the poles and they create spindle fibres.
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13
Q

What occurs in metaphase?

A
  • The spindle fibres pull the chromosomes to line up on the center of the cell called the equatorial plate.
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14
Q

What occurs in anaphase?

A

The Spindle fibres pull the sister chromatids apart towards the poles, the chromatids are now called chromosomes.

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15
Q

What occurs in telophase?

A

The nuclear membrane reforms, and chromosomes become chromatin and cytokinesis occurs

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15
Q

What is cytokinesis?

A

The dividing of the cytoplasm

16
Q

Where and why does mitosis occur in organisms?

A

Cells generally divide for the repair and growth of new cells, so mitosis will occur anywhere in the body a new cell is required. However, the more specialized the cells the fewer divisions will occur. So the skin of humans for example is where mitosis would occur, because skin cells are not specialized and as we are constantly getting cuts and brusies the repair of cells is nessasry.

17
Q

What are the major events of mitosis?

A

Interphase, prophase, metaphase, anaphase, and telophase.

18
Q

What are the major event of meisos?

A

Meiosis 1, Interphase, Prophase 1, Metaphase, Anaphase 1, Telophase 1, Meiosis 2

19
Q

How is cancer related to mitosis?

A

Cancer is caused by the uncontrolled and abnormal cell division that can cause tumours. So bad cells keep duplicating itself killing healthy cells and destroying the body.

20
Q

What is homologous chromosomes?

A

They are chromosomes that pair together (one from paternal and one from maternal) similar in shape, size, gene arrangement, and gene information.

21
Q

What are non-homologous chromosomes?

A

Chromosomes paired together that are different in shape, size, gene arrangement, and gene information.

22
Q

What is crossing over?

A

It is the exchange of genetic material between two homologous chromosomes.

23
Q

What happens at meiosis 1?

A

reduction in chromosome number

24
Q

What happens in Interphase (meiosis)

A

Same as mitosis

25
Q

What happens in prophase 1?

A
  • Homologous pairs come together in a process called synapsis, these pairs are called tetrads.
  • Crossing over happens (exchange of genetic info)
26
Q

What happens in Metaphase 1

A

Pairs independently assort on the equatorial plate.

27
Q

What happens at anaphase 1?

A

Pairs are separated and go to the poles

28
Q

What happens at Telophase 1?

A

cytokinesis occurs, and we now have two cells.

29
Q

What happens at meiosis 2?

A

The two cells become 4 haploid cells and it is the same as mitosis.

30
Q

What is the necessity for the reduction of chromosome number before fertilization?

A

As normal human beings, we receive 23 chromosomes from our mother and 23 from our father so we have a total of 46 chromosomes in total, we would not survive if we had 46 from both parents.

31
Q

What is spermatogenesis?

A

The production of sperm cells, when spermatagonia divide and differentiate into mature sperm cells. 4 sperm cells are produced and they are very small.

32
Q

What is oogenesis?

A

production and maturation of mature egg cells called an ova. One egg is produced it is large along with a few polar bodies

33
Q

What are fraternal twins?

A

This is when multiple ovulation occurs during the same menstrual cycle. Each egg is fertilized differently with separate sperms. (TWO EVERYTHING - almost like being pregnant twice)

34
Q

What are identical twins?

A

This is when pre-embryonic splitting occurs - same DNA, one house.

35
Q

What is nondisjunction

A

It is the failure of a pair of homologous chromosomes to separate properly during meiosis. This can lead to monosomy, where there is a single chromosome in place of a homologous pair. OR It can lead to trisomy, where there is an extra chromosome instead of a homologous pair.

36
Q

What is cloning?

A

It is the process of forming identical offspring from a single cell or tissue, it permits the production of offspring with characteristics identical to those of the parent.

37
Q

What are stem cells?

A

A cell that can arise from a cell different from itself

38
Q

Explain down syndrome

A

It is where there is an extra chromosome in the 21st chromosome pair.