Mitosis Flashcards
In which type of cells does mitosis occur?
Eukaryotes
What’s the outcome of mitosis?
A parent cell divides to form 2 genetically identical daughter cells (containing an exact copy of DNA).
When is mitosis needed?
Fr the growth of multicellular organisms (eg humans) and for repairing damaged tissues.
What is interphase?
G1 + S + G2
What happens in G1?
The cell carries out its normal activities.
New organelles produced.
DNA content: 20 arbitrary
What happens in S?
Cell replicates its DNA, ready to divide by mitosis.
Checked for errors.
DNA content: 40 arbitary.
What happens in G2?
Cell continues growing.
Cytoskeleton of cell breaks down and all of the protein microtubule components begin to reassemble into spindle fibres.
DNA content: 40 arbitrary.
What are the stages is mitosis?
Prophase, Metaphase, Anaphase, Telophase
PMAT
What happens in prophase?
- chromosomes first become visible, they condense; getting shorter and fatter.
- chromosomes move to poles of cell.
- from each of the centrioles, spindle fibres develop, which span the cell pole to pole
- nucleolus disappears
- nuclear envelope breaks down, leaving the chromosomes free in the cytoplasm
What happens in metaphase?
- chromosomes seen to be made up of 2 chromatids
- chromatids are joined by the centromere
- the spindle fibres are pulled along by the spindle apparatus and arrange themselves across the equator of the cell
What happens in anaphase?
- centromeres divides into 2, separating each pair of sister chromosomes
- spindles contract, pulling chromatids to opposite poles of the spindle which make chromatids appear V-shaped
- energy for this is provided by the mitochondria, which gather around the spindle fibres
What happens in telophase?
- chromatids reach the opposite poles on the spindle
- chromatids become longer and thinner and are new chromes again
- nuclear envelope forms around each group of chromosomes
- spindle fibres disintegrate
- nucleolus re-forms
- cytoplasm divides (cytokinesis) and there are now 2 daughter cells which are genetically identical to the original cell and each other.
How does cell division by non prokaryotes take place?
By binary fission