Mitosis Flashcards

1
Q

In which type of cells does mitosis occur?

A

Eukaryotes

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2
Q

What’s the outcome of mitosis?

A

A parent cell divides to form 2 genetically identical daughter cells (containing an exact copy of DNA).

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3
Q

When is mitosis needed?

A

Fr the growth of multicellular organisms (eg humans) and for repairing damaged tissues.

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4
Q

What is interphase?

A

G1 + S + G2

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5
Q

What happens in G1?

A

The cell carries out its normal activities.
New organelles produced.

DNA content: 20 arbitrary

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6
Q

What happens in S?

A

Cell replicates its DNA, ready to divide by mitosis.
Checked for errors.

DNA content: 40 arbitary.

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7
Q

What happens in G2?

A

Cell continues growing.
Cytoskeleton of cell breaks down and all of the protein microtubule components begin to reassemble into spindle fibres.

DNA content: 40 arbitrary.

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8
Q

What are the stages is mitosis?

A

Prophase, Metaphase, Anaphase, Telophase

PMAT

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9
Q

What happens in prophase?

A
  • chromosomes first become visible, they condense; getting shorter and fatter.
  • chromosomes move to poles of cell.
  • from each of the centrioles, spindle fibres develop, which span the cell pole to pole
  • nucleolus disappears
  • nuclear envelope breaks down, leaving the chromosomes free in the cytoplasm
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10
Q

What happens in metaphase?

A
  • chromosomes seen to be made up of 2 chromatids
  • chromatids are joined by the centromere
  • the spindle fibres are pulled along by the spindle apparatus and arrange themselves across the equator of the cell
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11
Q

What happens in anaphase?

A
  • centromeres divides into 2, separating each pair of sister chromosomes
  • spindles contract, pulling chromatids to opposite poles of the spindle which make chromatids appear V-shaped
  • energy for this is provided by the mitochondria, which gather around the spindle fibres
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12
Q

What happens in telophase?

A
  • chromatids reach the opposite poles on the spindle
  • chromatids become longer and thinner and are new chromes again
  • nuclear envelope forms around each group of chromosomes
  • spindle fibres disintegrate
  • nucleolus re-forms
  • cytoplasm divides (cytokinesis) and there are now 2 daughter cells which are genetically identical to the original cell and each other.
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13
Q

How does cell division by non prokaryotes take place?

A

By binary fission

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