Mitosis Flashcards
what is nuclear division called?
karyokinesis
what is cell division called?
cytokinesis
what happens in prophase?
♣ Chromosomes condense and centriole pairs separate and move towards opposite poles of the cell
• Spindle apparatus forms between them and the nuclear membrane dissolves
This allows spindle fibres to interact with chromosomes
what happens in metaphase?
♣ Centriole pairs now at opposite ends of the cell
• Fibres of the spindle apparatus attach to each chromatid at the kinetochore (protein location in the centromere)
o Spindle fibres align the chromosomes at the equator of the cell
♣ This forms the metaphase plate
what happens in anaphase?
♣ The centromeres split so that each chromatid has its own centromere
• This allows sister chromatids to separate
♣ Spindle fibres (composed of microtubules) shorten
• This pulls the chromatids towards the poles of the cell
what happens in telophase?
♣ Spindle apparatus disappears
♣ Nuclear membrane forms around each new set of chromosomes
♣ Each nucleus is diploid
Chromosomes uncoil, resuming their interphase form
what happens during cytokinesis?
♣ Near the end of telophase, cytoplasm (cytosol+organelles) divide into two daughter cells
♣ In animal cells a cleavage furrow forms and the cell membrane invaginates along the equator
In plant cells the cell plate forms which splits the tetraploid cell in half
what is interphase?
♣ A period of growth and chromosome replication
♣ A cell normally spends 90% of its life in interphase
• During this phase, cell performs its normal cellular functions
• After replication, the chromosomes consist of two identical sister chromatids
o Held together at a region called the centromere
• During interphase, individual chromosomes are not visible; the DNA is uncoiled and called chromatin
♣ Consists of three parts:
• G1
o Initiates interphase
o Active growth phase and can vary in length (from cell to cell or species to species?)
o Cell increases in size and synthesizes proteins
o The length of the G1 phase determines the length of the entire cell cycle
• S
o DNA synthesis
• G2
o Now the cell prepares to divide
o Cell grows and synthesizes proteins
o The last phase of the cell cycle is the M phase
♣ During this phase, mitosis or meiosis occurs