mitosis Flashcards
what are the 5 phases of mitosis?
1) prophase
2) metaprophase
3) mate phase
4) anaphase
5) telophase
prophase
chromatin condenses
sister chromatids appear
mitotic spindle forms
prometaphase
nuclear envelope fragments
microtubules enter nuclear area and attach to kinetochores
metaphase
chromosomes line up at metaphase plate
anaphase
sister chromatids separate and move to opposite ends of the cell
telophase and cytokinesis
2 daughter nuclei form
animals: cleavage furrow
plants: vesicles form cell plate
G1 checkpoint
most important
checks for cell size, growth factors, and DNA damage
if stopped cell goes into G0
G2
checks for completion of DNA replication and DNA damage
if stopped cell will undergo apoptosis
M (spindle) checkpoint
checks for microtubule attachment to chromosomes at the kinetochores at metephase
cyclins
controls cell cycle
cyclin dependent kinases are activated by cyclins