cell communication/transduction Flashcards

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1
Q

direct contact

A

cells must be touching

animals: gap junctions
plants: plasmodesmata

immune cells (antigens)

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2
Q

local regulators

A

messages travel a short distance

paracrine & synaptic signaling

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3
Q

long distance signaling

A

hormones

endocrine signaling

circulatory (insulin)

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4
Q

3 stages of cell signaling

A

1) reception

2) transduction

3) response

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5
Q

stage 1: reception

A

ligand binds to receptor and activates it

initiates transduction signal

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6
Q

plasma membrane receptors

A

most common

bonds to large, polar ligands

can’t go through membrane

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7
Q

intracellular receptors

A

found in cytoplasm or nucleus or target cell

travels through plasma membrane

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8
Q

stage 2: transduction

A

conversion of extracellular signal to an intracellular signal that will bring about a response

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9
Q

phosphorylation vs dephosphorylation in cells

A

phosph: relays signal

dephosp: shuts off pathways

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10
Q

second messengers

A

signal is amplified

help relay message and amplify response

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11
Q

stage 3: response

A

converts signal to a response

alters cell processes

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12
Q

2 main membrane receptors in animals

A

GPCRs: GDP -> GTP, G protein is inactive until bonded to GPCR

ion channels: gate opens or closes when ligand binds to receptor

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