mitosis Flashcards

1
Q

what does a cell have to do before it divides

A

replicate its DNA

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2
Q

what are homologous chromosomes

A

genetic info thats the same but from two different parents

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3
Q

what do non dividing chromosomes look like

A

single chromatids

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4
Q

what is the pinch in a 2 chromatid chromosome

A

centromere

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5
Q

what protein holds two chromatids together

A

kinetochore

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6
Q

what are the 4 steps to DNA replication

A

unwinding
unzipping
building new strands
repackaging

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7
Q

what unzips dna

A

dna helicase

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8
Q

what joins 2 strands of DNA

A

dna ligase

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9
Q

what are the three types of DNA mutation / error

A

insertion
substitution
deletion

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10
Q

what are the 3 phases of interphase

A

G1
S
G2

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11
Q

what happens in G1 (2)

A

growth and metabolism

building of organelles

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12
Q

what happens in the S phase

A

DNA replication

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13
Q

what happens in the G2 phase (3)

A

growth
microtubules are made
contractile ring making

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14
Q

prophase (2)

A

chromatin condenses
spindles form

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15
Q

metaphase

A

chromosomes line up at the metaphase plate

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16
Q

anaphase

A

chromosomes separate and go towards opposite poles

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17
Q

telophase / cytokinesis

A

two cells are formed

18
Q

where do microtubules form from

A

centriole

19
Q

what phase does the nuclear envelope break down

A

prophase

20
Q

what phase do microtubules depolymerize

A

anaphase

21
Q

what makes the cleavage furrow

A

actin and myosin

22
Q

what are 3 things that happen before a cell divides

A

enough cytoplasm
stimulated by growth factor
neighboring cells die

23
Q

when do cells stop dividing (2)

A

when theyre snug with their neighbors
growth/ nutrients are withdrawn

24
Q

what is contact inhibition

A

cells stop dividing because they come into contact with other cells

25
Q

what is one bad thing that can happen if cells start dividing or stop dividing when they aren’t supposed to

A

cancer

26
Q

when is the first checkpoint

A

G1

27
Q

when is the second checkpoint

A

G2

28
Q

when is the last checkpoint

what is it called

A

mitosis

M checkpoint

29
Q

what is cancer

A

unregulated cell growth

30
Q

what acts like breaks to slow down damaging mutations

A

tumor suppressors

31
Q

what needs two damaged copies to cause cancer

A

tumor supressor genes

32
Q

what acts like an accelerator to cause damage

A

proto-oncogenes

33
Q

what only needs one damaged copy to cause cancer

A

porto-oncogenes

34
Q

where are tumor suppressor genes found

A

the nucleus

35
Q

where are port-oncogenes found

A

cytoplasm

36
Q

what’s another name for genes

A

discrete factors

37
Q

what is genotype

A

genetic makeup

38
Q

what is phenotype

A

how genetic makeup is expressed

39
Q

when are alleles separated

when are they rejoined

A

gamete formation

fertilization

40
Q

is what Mendel assumed about recessive and dominant traits true about most genes

A

no

41
Q

polygenetic inheritance

A

determined from dominant and recessive alleles

42
Q
A