Missed From Robins Qs Flashcards
T or F: if bleeding stops within Seconds, then vasodilation is what stopped it.
True, the Neuro response and Endothelin are responsible for stopping bleeding initially
What does Robins call anti-cardiolipin Ab?
Lupus Anticoagulant
What do you give someone after they come in with a blood clot?
- what about to prevent a clot in the PTT path?
- t-PA is used to break up pre-existing clots because it activates plasmin which can cleave fibrin (into Fibrin Split products like D-dimers in DIC)
- Heparin is used to PREVENT not to break up clots in the PTT path
- Coumadin works on the PT (extrinsic path)
What do you expect to see in someone’s lungs if they just had an MI?
- what about if they had been in hypovolemic shock 2 days prior to lung biopsy?
Venous congestion in pulmonary capillary bed with Edema
**You would see the same thing with the Hypovolemic shock because the main point is the blood is not moving and edema results
Contents of ∂ granules.
- ADP and ATP
- Ca2+
- Histamine
- Serotonin
- Epinephrine
Where are arterial clots within the Abdominal Aorta likely to embolize to?
Anywhere south of where the primary thrombus formed due to the direction of bloodflow
Must also be found in an artery because embolus would not make it through a capillary bed
Why is infarction rare in the liver?
- Because it has a dual blood supply
What prevents downstream clotting in blood vessels?
- Prostacyclin (PGI2) release and NO release prevent downstream platelet adhesion and aggregation
Phlebothrombosis = Thrombosis in a vein
Phlebothrombosis = Thrombosis in a vein
Alcoholics will have problems with clotting due what?
Poor nutrition = lack of vit. K
Liver Dysfunction = lack of II, VII, IX, and X synthesis
Lack of VII can lead to bleeding problems
T or F: A positive skin test for candida means you’ve previously been infected with candida, and many healthy people will test positive.
True, but positive tests are likely to occur in people with immune deficiencies like IgA deficiency where it can more easily infect mucosal surfaces
IgE Fc binding to Mast cell causing degranulation is the most important aspect to fighting parasitic infections
IgE Fc binding to Mast cell causing degranulation is the most important aspect to fighting parasitic infections
Can complement proteins be depleted in immune complex hypesensitivities?
- explain.
Yes, complement components like C3 and C4 can get depleted because of deposition of all of the complement fixing antibodies on the vasculature
T or F: common gamma chain deficiency is autosomal recessive.
False, its X-linked
T or F: people with diffuse sceleroderma may develope malignant hypertension.
True, kidney damage in the diffuse form of this disease can cause elevated BP due to blockage of Glomerulus
