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Mısır Flashcards

1
Q

Fosfomycin interferes with
a) Membrane permeability
b) Protein synthesis
c) DNA synthesis
d) Metabolic processes
e) Cell Wall synthesis

A

e) Cell Wall synthesis

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2
Q

Allylamines

A)Inhibit squalene epoxidase

B)Disrupt mitotic spindle

C)Bind to fungal membrane

D)Disrupt nucleic acid and protein synthesis

E)Inhibit C14a demethylase

A

A)Inhibit squalene epoxidase

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3
Q

Hydrogen peroxide is

A)Antiseptic

B)Disinfectant

C)Antiseptic and disinfectant

D) Antiviral

E)Antiprotozoal

A

A)Antiseptic

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4
Q

Streptogramins are

A)A group of cyclic peptide antibiotics

B)Irreversibly bind to the 50S ribosomal subunit

C)Irreversibly bind to the 30S ribosomal subunit

D)Reveribly bind to the 70S ribosomal subunit

A

E)Cyclic peptide antibiotics that bind to the 50S ribosomal subunit

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5
Q

The neurotransmitter which is

released at motor end plate is

A)NF

B)NA

C)5HT

D)ACH

E)Nicotine

A

D)ACH

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6
Q

The action of tigecycline is

A)Bactericidal

B)Fungistatic

C)Bacteriostatic

D)Fungicidal

E)Antiviral

A

C)Bacteriostatic

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7
Q

Sulfonamides inhibit

A)Cell wall synthesis

B) Dihydropteroate synthetase

C)Dihydrofolate synthetase

D)Dihydrofolate reductase

E) Thymidylate synthase

A

C)Dihydrofolate synthetase

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8
Q

Aminoglycosides are

A)Natural antibiotics

B)Semi synthetic antibiotics

C)Synthetic antibacterial

D)Inhibitors of nucleic acid synthesis

E)Natural and semi-synthetic
antibiotics

A

E)Natural and semi-synthetic
antibiotics

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9
Q

The mechanism of quinoline is to

A) Interfere with heme polymerization

B)Inhibit mitochondrial processes

C)Produce free radicals

D)Inhibit dihydrofolate reductase

E)Inhibit nucleic acid synthesis

A

A) Interfere with heme polymerization

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10
Q

Fosfomycin interferes with

A)Protein synthesis

B)Cell wall synthesis

C)Membrane permability

D)DNA synthesis

E)Cell wall synthesis

A

B)Cell wall synthesis

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11
Q

Clavulanic acid + Sulbactam

A) Antistaphylococcal antibiotics

B)Antimalarial drug

C) B-lactamase inhibitors

D) Antipseudomonal antibiotics

E)Metabolic processes

A

C) B-lactamase inhibitors

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12
Q

Antimicrobials exhibiting a long PAE often require

A)Multiple dose

B)Less frequent dose

C)Continuous infusion dose

D)Single dose

E)Intermittent infusion dose

A

D)Single dose

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13
Q

Sypmtoms can be seen in a person exposed to sarin:

A)urine retention

B)mydriasis

C)constriction of pupils

D)dry mouth

A

C)constriction of pupils

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14
Q

influenze treatment:

A)amantadine

B)oseltamivir

A

B)oseltamivir

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15
Q

which of the following is an Anti motion sickness drug?

A)scopolamine

A

A)scopolamine

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16
Q

Which of the following is used in the treatment of ulcerative collitios?

A)sulphaguanidine

B)sulfasalazine

C)sulfadicramide

D)sulfacetamide

A

B)sulfasalazine

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17
Q

Which of the following is used as a disinfectant for endoscopic material ?

A)Phenol
B)Ethanol
C)Glutaraldehyde
D)Formaldehyde

A

C)Glutaraldehyde

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18
Q

Which of the following is used in the treatment of RESISTANCE STRAINS OF MALARIA?

A)atovaquone-proguanil +(quinine)

B)mefloquine

C)artemisin

D)pyrimethamine

A

A)atovaquone-proguanil

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19
Q

Aminoglycosides act as ?

A)Pae

B)concentration dependent

C)Pae+concentration dependent

A

C)Pae+concentration dependent

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20
Q

Which of the following inhibits DNA gyrase?

A)Sulfonamide

B)Aminoglycoside

C)fluoroquinolones

A

C)fluoroquinolones

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21
Q

72)Which action can’t be seen by ganglion blocking?

A)Tachycardia

C)Diarrhea

C)Urinary retention

D)Cycloplegia

A

C)Diarrhea

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22
Q

73)VRE can be treated with:

A)Chloramphenicol

B)Doxycycline

C) quinupristin/dalfopristin

D)High dose ampicillin

E)Ampicillin/Sulbactam

A

C) quinupristin/dalfopristin

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23
Q

Which of the following is used as an empiric medicine?

A)Ceftriaxone

B)Imipenem

C) ceftazidime

A

B)Imipenem

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24
Q

Polymyxin activity?

A)Gram -ve bacteria

B)gram +ve bacteria

A

A)Gram -ve bacteria

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25
Q

Hangisi crystalurinei engeller?-

adequate hydration and alkalinization of urine

A

adequate hydration and alkalinization of urine

26
Q

peptic ulcer (şıklarda pirenzepine falan var)?

pirenzepine

A

pirenzepine

27
Q

allylamines (şıklarda squalen oxidase var)?

inhibiting squalene epoxidase

A

inhibiting squalene epoxidase

28
Q

Penicillin mechanism of action ?

A

bactericidal and time-dependent

29
Q

Chloride bulunduran?

A

disinfetant

30
Q

Aplastic anemia ?

-chloramphenicol

A

chloramphenicol

31
Q

multidrug resistant p.falciparum malaria (şıklarda primetamin mefloquin var)?-

artemisinin

وبصير mefloquine

A

artemisinin

وبصير mefloquine

32
Q

30)fidoxamicin?— –

act on the sigma subunit of RNA polymerase

A

act on the sigma subunit of RNA polymerase

33
Q

muhtemel sorusu streptogramini soruyordu

acts on the 50S bacterial ribosome

A

acts on the 50S bacterial ribosome

34
Q

32)hangisi yanlıştır?-

somatic motor neurons do not have ganglia

A

somatic motor neurons do not have ganglia

35
Q

Which of the following receptors mediates the main effect of pilocarpine in the gastric tissues?

M1

A

M1

36
Q

62.Macrolides and………… prevent the continuation of protein synthesis

Lincosamides

A

Lincosamides

37
Q

Pyrimethamine as an antimalarial drug

A. Inhibits dihydrofolate reductase

B. Interferes with heme polymerization

C. Produces free fadicals

D. Inhibits dihydrofolate synthase

E. All

A

A. Inhibits dihydrofolate reductase

38
Q

Acyclovir is monophosphorylated by

A. Host cell kinases

B. DNA gyrase

C. Reverse transcriptase

D. Viral kinase

E. All

A

D. Viral kinase

39
Q

Ivermectin is

A. Antiseptics

B. Disinfectants

C. Ectoparaticides

D. Endoparacitides

E. C+D

A

E. C+D

40
Q

Immediate broad spectrum empiric therapy is initially used in critically ill patient in case of

Unidentified M.O.

A

Unidentified M.O.

41
Q

68.Amonoglycosides inhibit protein synthesis through binding to

A

30S ribosomal subunit + tetracycline

42
Q

Which drug has synergistic effect with 5-FC?

A

Amphotericin B

43
Q

The pharmacodynamics of polymixins is

A. Time dependent bactericidal

B. Concentration dependent, bactericidal

C. Interval dependent bactericidal

D. PAE

E. PAE+ concentration dependent bactericidal

A

B. Concentration dependent, bactericidal

44
Q

72.Fluorquionolons -hoca soruda FQs diye vermiş- inhibit topoisomerase II in:

A

Gram - bacteria

45
Q

which of the following leads to dysfunction of the kidney

Amphotericin B

A

Amphotericin B

46
Q

urinary tract infections is treated by:

A

Fosfomycin

47
Q

A rate limiting step in ACh synthesis?

Answer: choline

A

choline

48
Q

antimalirial drug that interfer with heme polymerization to hemozoin?
A)primquine
B)artemisin
C)chloroquine
D)atovaquone/proguanii

A

C)chloroquine

49
Q

Ivermectin mechanism of action ? Answer: Glutamate-gated Cl- channels

A

Glutamate-gated Cl- channels

Cl chloride

50
Q

Which of the following is used as a disinfectant for endoscopic material ?
A)Phenol
B)Ethanol
C)Glutaraldehyde
D)Formaldehyde

A

C)Glutaraldehyde

51
Q

which of the following is used in severe mushrooms toxication ?

A

Atropine

52
Q

Monobactams act by
A)Inhibiting protein synthesis
B)Inhibiting cell membrane function
C)Inhibiting nucleic acid function
D)Inhibiting nucleic acid synthesis
E)Inhibiting the synthesis of peptidoglycan layer of bacterial cell
walls.

A

E)Inhibiting the synthesis of peptidoglycan layer of bacterial cell
walls.

53
Q

Aminoglycosides…. -

Inhibitors of protein synthesis(30S)

A

Inhibitors of protein synthesis(30S)

54
Q

Cephalosporins…

a. Bactericidal and time independent

b. Destroys cell Wall

e. a+b

A

e. a+b

55
Q

Sulfonamides…

a. synthetic PABA

b. disulphonic acid ile etki etme

c.?

cevap: a+b+c

A

a+b+c

56
Q

Penicillins…

b. time independent bactericidal

d. Beta lactam antibiotics

cevap: b+d

A

cevap: b+d

57
Q

Hem exoerythrocytic hem gametocytic anti-malarial?

Primaquine

A

Primaquine

58
Q

Respiratory viral infections can be treated with

A) Acyclovir

B)Interferons

C) Nonnucleoside reverse transcriptase inhibitors

D) Neuraminidase inhibitors

E) CCR5 Antagonists

A

D) Neuraminidase inhibitors

59
Q

Which of the following is not in the penicillin classification?

A) Amoxicillin

B) Dicloxacillin

C) Ampicillin

D) Cefaclor

E) Piperacillin

A

D) Cefaclor

60
Q

Which of the following is not a featue of disinfectant for drinking water?
a) It cannot be detected in disinfected water
b) It should be easily stored, transported and easy to appy
c) The disinfectant must remain in the waterfor sufficent time
d) It should not harm people and pets
e) It should be cheap and safe

A

a) It cannot be detected in disinfected water

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