miscellaneous pharm Flashcards

1
Q

Are responses faster in the somatic nervous system or ANS?

A

somatic

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2
Q

what is the rate-limiting step in NE synthesis?

A

conversion of tyrosine to DOPA

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3
Q

What neurotransmitters couple to both ionotropic and metabotropic receptors?

A

Acetylcholine, GABA, glutamate, serotonin.

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4
Q

Why is atropine given in surgical procedures?

A

prevent activation of cardiac muscarinic receptors

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5
Q

tolterodin

A

muscarinic antagonist

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6
Q

oxybutynin

A

muscarinic antagonist

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7
Q

ipratropium

A

muscarinic antagonist

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8
Q

pyridostigmine

A

acetylcholinesterase inhibitor

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9
Q

pralidoxime

A

cholinesterase reactivator (antidote for organophosphate poisoning)

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10
Q

epinephrine

A

a1,a2,b1,b2 agonist

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11
Q

pseudoephedrine

A

indirect agonist

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12
Q

norepinephrine

A

a1,a2,b1 agonist

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13
Q

phenylephrine

A

a1 agonist

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14
Q

clonidine

A

a2 agonist

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15
Q

isoproterenol

A

b1/b2 agonist

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16
Q

dobutamine

A

b1 agonist

17
Q

dopamine

A

d1-d2 direct agonist plus indirect agonist

18
Q

doxazosin

A

a1 antagonist

19
Q

propranolol

A

b1/b2 antagonist

20
Q

metoprolol

A

b1 antagonist

21
Q

atenolol

A

b1 antagonist

22
Q

labetalol

A

a and b1/b2 antagonist

23
Q

curare

A

NMJ competitive blocker (non-depolarizing)

24
Q

atacurium

A

NMJ competitive blocker

25
rocuronium
NMJ competitive blocker
26
succinylcholine
NMJ depolarizing blocker
27
drug used to diagnose MG?
edrophonium
28
treatment for ALS?
riluzole (glutamate inhibitor)
29
treatment for HTN?
b1 blockers OR a1+b1 blockers
30
treatment for hypotensive shock?
a1 agonism (you want to vasoconstrict) or b1 agonism
31
what's responsible for smooth muscle relaxation in the bladder?
b2-3 agonism
32
what do you use for muscle relaxation in surgery?
cholinergic antagonists
33
what drugs may have the side effect of depressed mood-sleep disturbance?
beta blockers