miscellaneous pharm Flashcards

1
Q

Are responses faster in the somatic nervous system or ANS?

A

somatic

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2
Q

what is the rate-limiting step in NE synthesis?

A

conversion of tyrosine to DOPA

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3
Q

What neurotransmitters couple to both ionotropic and metabotropic receptors?

A

Acetylcholine, GABA, glutamate, serotonin.

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4
Q

Why is atropine given in surgical procedures?

A

prevent activation of cardiac muscarinic receptors

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5
Q

tolterodin

A

muscarinic antagonist

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6
Q

oxybutynin

A

muscarinic antagonist

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7
Q

ipratropium

A

muscarinic antagonist

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8
Q

pyridostigmine

A

acetylcholinesterase inhibitor

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9
Q

pralidoxime

A

cholinesterase reactivator (antidote for organophosphate poisoning)

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10
Q

epinephrine

A

a1,a2,b1,b2 agonist

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11
Q

pseudoephedrine

A

indirect agonist

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12
Q

norepinephrine

A

a1,a2,b1 agonist

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13
Q

phenylephrine

A

a1 agonist

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14
Q

clonidine

A

a2 agonist

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15
Q

isoproterenol

A

b1/b2 agonist

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16
Q

dobutamine

A

b1 agonist

17
Q

dopamine

A

d1-d2 direct agonist plus indirect agonist

18
Q

doxazosin

A

a1 antagonist

19
Q

propranolol

A

b1/b2 antagonist

20
Q

metoprolol

A

b1 antagonist

21
Q

atenolol

A

b1 antagonist

22
Q

labetalol

A

a and b1/b2 antagonist

23
Q

curare

A

NMJ competitive blocker (non-depolarizing)

24
Q

atacurium

A

NMJ competitive blocker

25
Q

rocuronium

A

NMJ competitive blocker

26
Q

succinylcholine

A

NMJ depolarizing blocker

27
Q

drug used to diagnose MG?

A

edrophonium

28
Q

treatment for ALS?

A

riluzole (glutamate inhibitor)

29
Q

treatment for HTN?

A

b1 blockers OR a1+b1 blockers

30
Q

treatment for hypotensive shock?

A

a1 agonism (you want to vasoconstrict) or b1 agonism

31
Q

what’s responsible for smooth muscle relaxation in the bladder?

A

b2-3 agonism

32
Q

what do you use for muscle relaxation in surgery?

A

cholinergic antagonists

33
Q

what drugs may have the side effect of depressed mood-sleep disturbance?

A

beta blockers