Miscellaneous enzymes Flashcards
A phosphoric monoester hydrolase
Nucleotidase (5’N)
- Predominantly found in the liver
- Marker for the hepatobiliary and infiltrative lesions of the liver
Nucleotidase
T/F: Nucleotidase can also serve as liver enzyme marker
TRUE
- Index of parenchymal function
- Used to monitor the effect of muscle relaxants (succinylcholine) after surgery
Cholinesterase / Pseudocholinesterase
Marker for insecticide or pesticide poisoning (organophosphate)
Cholinesterase / Pseudocholinesterase
Angiotensin-Converting Enzyme is also known as
Peptidyldipeptidase A or Kininase II
The active form for angiotensin
Angiotensin 2
Increase ACE is seen on
Sarcoidosis, acute and chronic bronchitis, and leprosy
Main source of ACE
Macrophage and Epithelioid cells
A protein carrying the copper in the plasma
Ceruloplasmin
Marker for Wilson’s dse (hepatolenticular dse)
Ceruloplasmin
For hepatobiliary dse
Ornithine Carbamoyl Transferase (OCT)
Important to maintain NADPH in the reduced form in the erythrocyte
G6PD
Stabilizes cell membrane and protect it from lysis
NADPH
Measure among babies (A newborn screening marker)
G6PD
G6PD is seen on what organs?
Adrenal cortex, spleen, RBC, and lymph nodes
Deficiency can lead to drug-induced hemolytic anemia (primaquine, antimalaria drug)
G6PD
Increased G6PD is seen on
MI, Megaloblastic anemia