Enzyme Classification and Nomenclature

Question 1

Responsible for naming and classifying enzyme

Answer 1

Enzyme commission of IUB (International Union of Biochemistry)

Question 2

Defines the substrate acted on the reaction catalyze and possibly coenzyme involved (long name and complete)

Answer 2

Systematic name

Question 3

Usable name or trivial name

Answer 3

Recommended Name

Question 4

Composed of 4 digits

Answer 4

EC (Enzyme Commission) Numerical code

Question 5

Represent the enzyme class

Answer 5

First digit

Question 6

Represent enzyme subclass

Answer 6

Second digit

Question 7

Represent the enzyme sub-sub class

Answer 7

Third digit

Question 8

Enzyme serial number specific to the enzyme sub-sub class

Answer 8

Fourth digit

Question 9

Long name of Acid phosphatase

Answer 9

Orthophosporic monoester phosphohydrolase (acid optimum)

Question 10

E.C code for Acid phosphatase

Answer 10

E.C.3.1.3.2

Question 11

Long name for Amylase

Answer 11

1-4-D-Glucan-Glucanohydrolase

Question 12

E.C code for amylase

Answer 12

E.C.3.2.1.1

Question 13

Long name for Alanine Amino transferase

Answer 13

L-alanine:2 Oxaglutarate aminotransferase

Question 14

E.C code for Alanine Amino transferase

Answer 14

E.C.2.6.1.2

Question 15

• Catalyze redox reaction between two substrates
• Utilize coenzymes and a part of oxidoreductase activity (NAD and NADP)

Answer 15

Oxidoreductase

Question 16

The most commonly transferred atom in the
oxidoreductase reaction

Answer 16

Hydrogen Ion

Question 17

A- +B→A+B-

Answer 17

Oxidoreductase reaction

Question 18

Example of Oxidoreductase reaction

Answer 18

Dehydrogenase (LDH and G6PD)

Question 19

Catalyze the transfer of a particular chemical group whether it is phosphate and methyl group other than hydrogen ions between two substrates

Answer 19

Transferases

Question 20

A–X+B→ A+B-X

Answer 20

Transferase reaction
A and B are substrate
X - chemical group

Question 21

Examples of transferase

Answer 21

Alanine Aminotransferase (ALT), Aspartate Aminotransferase (AST), gamma- glutamyltransferase (GGT) and Kinase

Question 22

A specific type of transferase that catalyzes the reaction of a phosphate group from one substrate to another

Answer 22

Kinase (CK)

Question 23

Enzymes that catalyze the hydrolysis of various chemical bonds

Answer 23

Hydrolases

Question 24

For hydrolase to function, there is a need for

Answer 24

Water

Question 25

A-B+H2O→A-OH+B-H

Answer 25

Hydrolase reaction

Question 26

Example of Hydrolases

Answer 26

Amylase, lipase and phosphatases

Question 27

Enzymes that catalyze the removal of chemical groups without water or hydrolytic mechanism

Answer 27

Lyases

Question 28

T/F: In lyases there is no need for hydrolysis

Answer 28

TRUE

Question 29

The product of lyases retain its

Answer 29

Double bond

Question 30

cAMP means

Answer 30

cyclic adenosine monophosphate

Question 31

Ppi means

Answer 31

Intermediate diphosphate

Question 32

Example of Lyases

Answer 32

Fructose biphosphate aldolase (ALS)

Question 33

Catalyze interconversion of geometric, optical, and positional isomers

Answer 33

Isomerases

Question 34

Give the reaction for Isomerase

Answer 34

A→B

Question 35

Example of Isomerase

Answer 35

Triphosphate isomerase (TPI)

Question 36

Catalyzes joining of 2 substrate molecules coupled with pyrophosphate bond in ADP

Answer 36

Ligases

Question 37

Example of Ligase

Answer 37

Glutathione Synthetase (GSH-S)