Miscellaneous Flashcards
Blood components available from donation (4)
RBC, FFP, platelets and cryoprecipitate
On which chromosome is the ABO gene located
9
Genotype for group O
OO
Genotype for group A
AA or AO
Genotype for group B
BB or BO
Genotype for group AB
AB
What is Landsteiners law
When an individual lacks the A or B antigen, the corresponding antibody is produced in their plasma
Consequence of giving a patient blood that is not compatible
Antibodies cause haemolysis of red blood cells
Antibodies present in plasma of patients with group A blood
Anti-B
Antibodies present in plasma of patients with group B blood
Anti-A
Antibodies present in plasma of patients with group AB blood
Neither
Antibodies present in plasma of patients with group O blood
Anti-A and anti-B
Genotype for RhD+
DD or Dd
Genotype for RhD-
dd
Indications for red cell transfusion (2)
Major bleeding or symptomatic anaemia
Indications for platelet transfusion (2)
Prophylaxis in patients with bone marrow failure OR in thrombocytopenic patients
Treating bleeding in thrombocytopenic patients
Indications for FFP transfusions (2)
Treatment in bleeding or prior to surgery in patients with coagulopathy
Management of massive haemorrhage
When is an FFP transfusion NOT indicated (2)
In absence of bleeding
Planned procedure even if coagulation screen is abnormal
What needs to be done to blood given to immunocompromised patients
Irradiation
When do non-haemolytic febrile transfusion reactions tend to occur
30-60 mins after transfusion has begun
White out on CXR following transfusion
Transfusion related acute lung injury
What is the universal blood donor
O-
What transfusable blood product has the shortest shelf life
Platelets