Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

1. Psych Exam 1 > Misc Pharm > Flashcards

Misc Pharm Flashcards

You may prefer our related Brainscape-certified flashcards:
Psychology 101 flashcards GRE® Psychology flashcards
1
Q

effective topical rx for actinic keratoses. causes fast proliferating cell to die thymidine-less death. necrosis and erosion leads to re-epithelialization

A

5-FU

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

which glucocorticoids should be added to the face?

A

low potency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

synthetic topical antimycotic agent w broad spectrum

A

ciclopirox

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

macrolide that is not CYP450 inc. taken up by phagocytes and released @ site of infection

A

azithromycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

topical antimicrobial used to rx acne. skin irritant and may bleach things

A

benzoyl peroxide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

blocking of this radiation was only goal of sun screen. can treat psoriasis

A

UVB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

wound covering preferred during grans/re-epitheliazation phases

A

low adherence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

otc drug used to treat jock itch. inactive to yeast

A

tolnaftate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

broad spectrum antimicrobial widely used in homes and hospitals bc of low skin irritability

A

chlorhexidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

for best healing keep wounds

A

moist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

radiation that doesnt cause sunburn, but does cause aging and carcinogenesis. used to rx psoriasis w psoralens under strict supervision

A

uva

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

topical retinoid. alters gene expression to nml keratinization and reduce comedomes

A

t-retinoid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

good distractior that does not promote wound healing

A

egf

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

peptide abx w efficacy against g- including pseudomonas, detergent like effects that damage cell membrane

A

polymixin B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

oral insecticide to Rx ectoparasites. bind glutamate act Cl channels to hyperpolarize membrane

A

ivermectine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

class of adrenergic applied topically to rx rosacea

A

alpha

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

organophosphate AchE inh that kills ectoparasites

A

malathion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

synthetic insecticide like chrysanthemums. blocks membrane repolarizing

A

permethrin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

old remedy for psoriasis

A

tar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

late choice to rx ectoparasites. works by disrupting GABAergic transmission

A

lindane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

tetracycline to rx acne. can cause dark pigmentation in skin and sclera

A

minocycline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

class of antifungals that block ergosterol synth

A

imidazoles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

prototypical non-steroid androgen antag, used in prostate cx and male pattern baldness in women

A

flutamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

inh of the signalling pathway can rx advanced BCC

A

hedgehog

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

potent vdl due to hyperpol via act of K channels. apply topically to grow hair

A

minoxidil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

systemic therapy to rx tinea versicolor

A

fluconazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

formation of these after drug application to skin can prolong half-life long enough for 1/day dosing

A

reservoir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

antifungal with topical effects limited to candida. may stain skin yellow

A

amphotericin B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

platelet derived gf. stimulates diabetic ulcer repair. use w caution bc cx risk

A

becaplermin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

anti-inflamm agent w keratolytic effects. dissolves intracellular cement and rx acne

A

salicylic acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

peptide abx w g+ act and some anaerobes. only topical application bc systemic toxicity

A

bacitracin

32
Q

rx for actinic keratosis derived from Euphorbia peplus. causes chemoablation and neutrophil mediated ab dependent cytotoxicity – eliminating remaining tumor cells

A

ingenolmebutate

33
Q

blocks conversion of testosterone to androgen DHT. Rx for male baldness and 2nd line in women

A

finasteride

34
Q

agents like: glycerin, lecithin & propylene glycol. draws water out of outer layer of skin.

A

humectants

35
Q

cyclosporin and tacrolimus are among these agents. revolutionized transplant therapy bc didn’t cause bone marrow suppression

A

calcineuron inh

36
Q

ab against IL12 and IL23 to rx psoriasis

A

ustekinumab

37
Q

biologic dmard directed against IL17a. rx for psoriasis

A

secukinumab

38
Q

component of plant defenses against bacteria. active against P. acne

A

azaleic acid

39
Q

macrolide abx, used for topical and systemic rx of acne. well known CYP450 inh

A

erythromycin

40
Q

topical agent used for jock itch, athletes foot, and nail infections.

A

terbinafine

41
Q

topical immune response modifier used to treat actinic keratoses and BCC/SCC. also used to rx genital warts

A

imiquimod

42
Q

oral retinoid for severe acne.

A

isoretinoid

43
Q

oral PDE4 inh used for plaque psoriasis

A

apremilast

44
Q

partial agonist at CXCR4, for homing of stem cells.

A

plerixafor

45
Q

severe if count below 500. sx include sore mouth, low grade fever, and severe swallowing pain.

A

neutropenia

46
Q

causes n/v, diarrhea, and constipation. heart burn, and dark stool

A

iron tablets

47
Q

antiarrythmic, causes drug induced thrombocytopenia

A

quinidine

48
Q

ex of oral iron pill

A

ferrous sulfate

49
Q

recombinant gm-csf acts in bone marrow to inc neutrophils, eosinophils, and monocytes.

A

sargramostim

50
Q

recombinant IL11. early agent that inc platelet levels

A

oprelvekin

51
Q

recombinant g-csf. inc growth of neutrophil progenitors and mature ones

A

filgrastim

52
Q

ae: fluid retention, dyspnea bc of granulocyte sequestration in pulm circulation, “gasping syn” in infants

A

sargramostim

53
Q

reason to admin filgrastim w/or w/out plerixafor. mobilizes hematopoetic progenitors

A

leukopheresis

54
Q

reason oxygen can be stripped from blood and stored in muscle

A

myoglobin

55
Q

AE of filgrastim, sargramostim, and EPO

A

bone pain

56
Q

aka c-kit. potent syndergistic effects on progenitor cells. cant be used bc of mast cell effects

A

stem cell factor

57
Q

type of anemia assc w cephalosporins and penicillin

A

hemolytic

58
Q

anemia where rbc dbl protein but cant make DNA

A

macrocytic

59
Q

mc cause of drug-induced thrombocytopenia

A

heparin

60
Q

can be severe w oral iron admin

A

gi distress

61
Q

needed to make methionine from homocysteine and tetrahydrofolate from 5-methylTHF

A

vit b12

62
Q

sx that justifies parenteral vit b12

A

neuro

63
Q

use for iv admin of iron if intolerance to oral forms

A

iron dextran

64
Q

gi ae of folate def

A

mouth ulcers

65
Q

orally active non-peptide thrombopoietin agonist for Rx of ITP and thrombocytopenia of hep C

A

eltrombopag

66
Q

iron chelator

A

deferoxamine

67
Q

using this for analgesia can lead to vit b12 def

A

nitrous oxide

68
Q

atypical form of this is indication for eculizumab

A

HUS

69
Q

life-threatening ae of chemo.

A

neutropenic fever

70
Q

aa sequence identical to epo. treat anemia 2nd to CKD or chemo

A

epoetin alfa

71
Q

prevents formation of MAC to treat PNH (CD59 or DAF def)

A

eculizumab

72
Q

nanoparticle used to treat iron def

A

ferumoxytil

73
Q

reduces bioavailability or oral iron

A

enteric coating

74
Q

indication for romiplostin/eltrombopag after 1st choice fails

A

ITP

75
Q

peptibody that stimulates thrombopoietin receptor to promote platelet production

A

romiplostim

1. Psych Exam 1 (22 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions