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Heme GI > Misc > Flashcards

Misc Flashcards

1
Q

iso chromosome

A

breaks at centromere

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2
Q

FISH

A

detect number and location of specific DNA sequences

  • doesn’t need a dividing cell
  • denature and hybridize
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3
Q

Dual color dual fusion FISH probe

A

1 red, 1 green, 2 fusions = translocation

2 red, 2 green = normal

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4
Q

Dual color, break apart FISH probe

A

2 Fusion = normal

1 fusion, 1 red, 1 green = translocation

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5
Q

EDTA and ACD function

A

serve as anticoagulants in blood

- can work for nucleic acid isolation

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6
Q

sucralfate

A

H2 receptor agonist

Treats GERD

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7
Q

Prokinetics

A

H2 receptor agonist

Treats GERD

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8
Q

Eikenella

A

bacteria associated with human bites

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9
Q

Capnocytophaga

A

bacteria associated with dog bites

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10
Q

Lactoperoxidase

A

enzyme in saliva that generates thiocyanate

- toxic to bacteria in the mouth

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11
Q

lactoferrin

A

binds iron so bacteria can’t use it

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12
Q

What area allows for the feeling of fullness when the stomach expands?

A

the fundus

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13
Q

What do chief cells secrete?

A

pepsinogen

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14
Q

What do parietal cells secrete?

A

HCl

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15
Q

What do D cells secrete?

A

somatostatin

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16
Q

What do G cells secrete?

A

Gastrin

17
Q

What is the MOA H. pylori?

A

inflammation of the antrum leading to D cell inhibition and decrease of somatostatin –> inc HCl = duodenal ulcer

18
Q

Peptic Ulcer symptoms

A

dyspepsia
abdominal pain
heartburn
complications

19
Q

Reflux disease symptoms

A

dyspepsia
dysphagia
heartburn
complications (dental, barretts esophagous)

20
Q

What do you use to treat mild reflux esophagitis?

A

H2 antagonist

21
Q

What do you use to treat severe reflux esophagitis?

A

proton pump inhibitor

22
Q

If h pylori turns into pan gastritis, what cancer is it prone to?

A

Gastric carcinoma

23
Q

If H pylori turns into antral gastritis, what is it prone to cause?

A

Duodenal ulcer

24
Q

If H. pylori leads to an increase of proliferating B cells, what cancer is it prone to?

A

MALT Lymphoma

25
Q

How do you treat patients with H. pylori and a peptic ulcer?

A

Triple and Quadruple therapy

Heme GI (14 decks)

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