Misc Flashcards
- Causes of erythema mutliforme
lamotrigine
. Obese, NIDDM ♀ with abnormal LFT’s →
NASH (non-alcoholic steatotic hepatitis)
Fluctuating level of conciousness in elderly plus/minus deterioration →
chronic
subdural. Can last even longer than 6 months
. Sensitivity →
TP/(TP plus FN)
- Ipsilateral ataxia, Horners, contralateral loss pain/temp →
PICA stroke (lateral medulary
syndrome of Wallenburg)
yperprolactinemia (gallactorrohea, amenorrohea, low FSH/LH) → causes are:
causes are:
(metoclopramide, chlorpromazine, cimetidine NOT TCA’s), pregnancy, PCOS, pit
tumor/microadenoma, stress.
. Episodic headache with tachycardia →
Pheochromocytoma
Diagnosis of CLL →
immunophenotyping NOT cytogenetics, NOT bone marrow
Pancytopenia with raised MCV →
check B12/folate first (other causes possble, but do
this FIRST). Often associayed with phenytoin use → ↓ folate
.Prognostic factors for AML →
bm karyotype (good/poor/standard) → WCC at
diagnosis.
.Pancytopenia with raised MCV →
check B12/folate first (other causes possble, but do
this FIRST). Often associayed with phenytoin use → ↓ folate
Anosmia, delayed puberty →
Kallmans syndrome (hypogonadotrophic hypogonadism)
. Commonest finding in G6PD hamolysis →
haumoglobinuria
Flank pain, urinalysis:blood, protein →
renal vein thrombosis. Causes: nephrotic
syndrome, RCC, amyloid, acute pyelonephritis, SLE (atiphospholipid syndrome which is recurrent thrombosis, fetal loss, dec plt. Usual cause of cns manifestations assoc with LUPUS ancoagulant, anticardiolipin ab)
Hypothermia, acute renal failure →
rhabdomyolysis (collapse assumed)
Burning, Pain, numbness anteriolateral thigh →
meralgia paraesthesia (lat cutaneous
nerve compression usally by by ing ligament)
Diagnosis of hemochromatosis:
screen with Ferritin, confirm by tranferrin saturation,
genotyping. If nondiagnostic do liver biopsy 0.3% mortality
.40 mg hidrocortisone divided doses (bd) →
10 mg prednisolone (ie. Prednislone is x4
stronger)
Diptheria →
exudative pharyngitis, lymphadenopathy, cardio and neuro toxicity.
Indurated plaques on cheeks, scarring alopecia, hyperkeratosis over hair follicles
→
Discoid LUPUS
Wt loss, malabsoption, inc ALP →
pancreatic cancer
Fever, lymphadenopathy, lymphocytosis, pharygitis →
EBV → heterophile antibodies
GI bleed after endovascular AAA Surgery →
aortoenteric fistula
Functional hypogonadotrophic hypogonadism →
amennorhea. LH and FSH both low. All other hormones are usually normal. Ferritin low.
Reiters Syndrome –
arthritis, uveitis, urethritis – Chlymidia, campylobacter, Yersinia, SALMONELLA , Shigella. Balanisits.
PKD –
aut dom Chr 16/4 assoc berry aneurysm, mitral/aortic regurg
Diag of PKD →
renal US even if think anorexia nervosa
Porphyria –
photosensitivity, blisters, scars with millia, hypertrichosis
Vitiligo –
commonest assoctions pernicious anemia → type 1 DM , autoimmune
addisons, autoimmune thyoid dx
Peripheral neuropathy –
a) B12 – rapid, dorsal columns (joint pos, vibration), sensory
ataxia, pseudoathetosis of upperlimbs b) diabetic – slow, spinothalamic (pain, temp?)
c)alcohol – slow progressive, spinothalamic d) Pb – motor upper limbs
CNS abnormalities in HIV:
: toxoplaasmosis (ring enhancing), lymphoma (solitary lesion). HIV encephalopathy, progressive multifocal leucoencephalopathy (PML –
demylination in advanced HIV, low attenuation lesions)
Travellers diarrohea:
chronic (>2 WEEKS) giardia (incidious onset rx. Metronidazole),
SALMONELLA (serious systemic illness), E.coli (rx. Ciprofloxacin) , Shigella
Renal syndrome –
minimal change disease, membanous, IgA nephropathy, post-
streptococcal.
Thyroid Malignancy –
tend to be non-functional, anaplastic has worse prognosis, local
infiltration → dysphagia, vocal cord paralysis
. Silvery white scale →
PSORIASIS
Hypopigmented →
vitiligo/pityriasis versicolor
Pretibial myxedema →
Graves (NOT lid lag, NOT exopthalmus)
R. Arthritis with nephritic syndrome →
looks for amyloidosis, even by rectal biopsy.
Cushing investigation
Overnight Dexamethasone Test
Cushing- vs. Pseudo-cushing
insulin Stress Tes
Acromegaly
Oral Glucose Tolerance Test