Minerals Flashcards

1
Q

DRV for iodine?

A

-RNI: 140ug Per day
-LRNI-70ug Per day

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2
Q

Function of iodine in body

A

-needed for production of thyroid hormones (thyroxine and triiodothyronine
(thyroid gland traps and concentrates iodine from blood stream)

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3
Q

What can happen if there is iodine deficiency?

A

-goitre- An enlargement of the thyroid gland
-Severe Iodine deficiency = thyroid hormone deficiency
-Mild deficiency associated with infertility In both men and women

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4
Q

symptoms of goitre?

A

tiredness, weight gain, poor
concertation

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5
Q

Effect of iodine deficiency in children?

A

-Severe-cretinism
-mild deficiency in pregnancy- cause reduced IQ in pregnancy

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6
Q

Symptoms of cretinism in children?

A

-impaired mental & physical development in the womb or early life
-Stunted growth
-Impaired function of many organs
-Severe mental retardation

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7
Q

Describe the global variation in iodine content/ consumption?

A

-areas close to the sea/ocean have iodine rich soil So plants grown in these areas have higher iodine content.
-Land locked areas (mountainous /away from the sea) have a lower iodine content.

-many countries have salt iodization programs increasing consumption

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8
Q

Which group of people is iodine consumption particularly important for?

A

-Pregnant women

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9
Q

Sources of iodine

A

-milk and sea fish

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9
Q

Effect of plant milks on iodine consumption

A

-Increase on non dairy milk consumption in UK however although they are fortified with some nutrients no plant milks are fortified with iodine
-Therefore vegans have high risk of iodine deficiency

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10
Q

Why are vegetarians encouraged to include seaweed in their diet?

A

-Contains iodine
-however some contain an excessive amount which can be harmful to health
-seaweed consumption is not recommended during pregnancy due to possibility of toxins

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11
Q

Who should be taking iodine supplements?

A

-People who avoid milk, dairy foods and sea fish in their diet
-mean and women prior to conception
-Essential to women during pregnancy and lactation

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12
Q

Name the major minerals

A

Sodium, potassium, magnesium, calcium, phosphorus, sulfur, chloride

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13
Q

Difference between trace minerals and major minerals?

A

-Body needs less of trace minerals
-major minerals are Present in body tissues at concentrations >50 mg/kg and trace are Present in body tissues at concentrations <50 mg/kg

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14
Q

Name the trace minerals/ elements

A

Chromium, manganese, iron, cobalt, molybdenum, copper, zinc, fluoride, iodine, selenium, silicon, tin, arsenic, nickel…

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15
Q

Sodium functions

A

-helps uptake of nutrients and water in cells
-helps muscles contract
-helps nerves carry messages between brain and body
-balances bodies fluids and regulates blood pressure

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16
Q

Why is calcium and iron absorption regulated differently to other minerals?

A

-regulated according to the needs of the body.
-Calcium absorption is related to the amount of specific binding protein within the enterocyte.
-The concentration of the calcium binding protein (Calbindin), which regulates calcium uptake from the gut, is secondary to vitamin D levels.

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17
Q

Describe the presence of calcium in the body

A

-most abundant mineral in animal tissues
-found in blood and other tissues

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18
Q

Calcium functions

A

Bone structure
Nerve function
Blood clotting
Muscle contraction
Cellular metabolism

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19
Q

Sources of calcium

A

Milk and dairy products
(High bioavailability (fortified with vitamin D))
Green leafy vegetables
Poor absorption
Fish with bones
Fortified juice/cereal

20
Q

What 3 hormones are involved in regulation of calcium?

A

Vitamin D3 (from kidney)
Parathyroid hormone (PTH)
(from parathyroid gland)
Calcitonin
(from thyroid gland)

21
Q

Describe the regulation of calcium homeostasis?

A

1-thyroid gland secretes calcitonin
-this leads to decreased calcium absorption in SI, decreased bone breakdown, increased calcium excretion in urine
2-blod levels of calcium return to normal
3-parathyroid glands release parathyroid hormone (PTH)
4-PTH stimulates conversion to calcitriol in the kidneys
4-Together Calcitriol and PTH stimulate increased calcium absorption in SI, increased bone breakdown and decreased calcium excretion
5-blood levels of calcium return to normal

22
Q

Effect of calcium deficiency?

A

-rickets
-osteomalacia (osteoporosis)

23
Q

What is osteoporosis?

A

-at around age 40 bone breakdown exceeds formation causing large decrease in bone mass

24
How can osteoporosis be prevented?
-Maintain adequate calcium and vitamin D intake -Perform weight-bearing exercise -Hormone Replacement Therapy
25
What chronic diseases can milk and calcium consumption reduce the risk of
Degenerative diseases Heart disease Lowers blood pressure Cancer Breast, prostate, colon Obesity
26
what are trace elements?
-Inorganic elements occur in nature and are found in water, soil and rock -Taken up by plant roots and hence into animals and humans -exist in the body as Biological components – in the skeleton, in haemoglobin, in thyroid hormones and in many enzymes
27
where can iron be found in the body?
-haemoglobin of red blood cells (60%) -myoglobin in muscles (8%) -transferrin (2%) -stores in liver (25%) -enzymes (5%)
28
how is iron lost from the body?
from cell losses from the skin and interior surfaces of the body such as the intestines, urinary tract and airways and through bleeding.
29
why is there a high iron requirement in newborns and infants?
-As they have no iron stores and this a period of rapid growth -iron deficiency can be reduced at this stage due to most infant cereals as they are fortified with iron
30
why is there an increased iron requirement in adolescents?
-Period of rapid growth -also during puberty there's an increase in haemoglobin mass and concentration increasing requirements
31
what does iron absorption depend on?
-The type of iron (ahem or non-haem) -2 separate types of receptor are used on the mucosal cells and are absorbed in different efficiencies
32
Describe haem iron absorption?
-found in meat and meat products and is derived from haemoglobin and myoglobin in meat -absorption is 10-30% -generally not affected by diet -more fast absorbed
33
Describe Non haem iron absorption
-main form of dietary iron and is found in cereals, vegetables, pulses, beans, fruits etc. -is in the form of iron salts, iron in other proteins & iron derived from processing or storage methods. -only 2-10% consumed can be absorbed -more slow absorbed -is affected by other components in diet
34
What factors can inhibit non-haem iron absorption?
-Phytates – found in plant cells. In western-type diets 90% of phytates originate from cereals. -Polyphenols – are part of the plant’s defence mechanism against insects, animals and man. E.g. tannin. -Calcium– in the form of dairy products such as milk and cheese. Also inhibits haem iron absorption.
35
what factors can enhance non-haem iron absorption?
-Ascorbic acid/vitamin C – Most potent enhancer. It does this by converting the iron from ferric (Fe3+) to ferrous (Fe2+) forms. -Meat, fish & seafood – In addition to providing haem iron themselves they also promote the absorption of non-haem iron. -alcohol
36
37
what is bioavailabitly?
the degree to which a substance is available to the body.
38
what non-heme iron sources have a high bioavailability?
-lemons, oranges, tomatoes -brocolli, cabbage -white whine -fish, meat, poultry
39
Functions of iron?
-It is part of haemoglobin which carries oxygen to body tissues -It helps store oxygen in muscle cells through myoglobin -It is a component of various tissue enzymes involved in energy production and brain function.
39
Symptoms of iron defiiciency?
Fatigue Restlessness Impaired work performance
39
Cereals contain which form of iron?
Non-haem iron
39
Main predictors of a low iron status?
-women carrying out menstruation -no consumption of red meat
39
what are the 3 stages that adequate iron status can progress to iron deficiency then anaemia?
1-Depletion of storage iron 2-Decrease in transported iron in transferrin proteins 3-Reduction in red blood cell formation (anaemia)
39
Main predictors of a good iron status?
Regular consumption of raw vegetables (salads) Regular consumption of red meat
40
How can excessive iron absorption occur and what can this cause?
-consumption of iron supplements -alcohlics- consuming large amounts of wine with high iron content -can cause tissue damage
40
How can vegetarians help ensure they have a sufficient iron absorption?
-fresh fruit/ juice with meals help with absorption -salad veg contain vit C which helps absorption -green leafy veg is good source of iron -avoid drinking tea with meals as this reduces iron absorption
41
how can iron toxicity be caused by genetic disorders?
-iron absorption isn't regulated due to disease eg. idiopathic hereditary hemochromatosis -sufferers must avoid iron fortified foods
42