Mineralization Of Tooth

Question 1

Enamel is mineralized purely by what mechanism

Answer 1

Heterogenous mineralization

Question 2

What are the matrix producing cells

Answer 2

Osteoblasts, odontblasts and ameloblasts

Question 3

Basic mechanism for mineralization

Answer 3

Matrix vesicle-mediated mineralization

Heterogenous mineralization or epitaxy

Question 4

These cells controls the transport of calcium ions into the matrix

Answer 4

Matrix producing cells

Osteoblasts, odontoblasts and ameloblast

Question 5

Why hydroyapatite cannot be precipitated directly?

Answer 5

Beacuse it is too complex, we must first precipitate it to a less stable, simpler calcium phosphate

Question 6

Simpler form of hydroxyapatite

Answer 6

Brushite

Question 7

These vesicles provide a controlled micro-environment to concentrate calcium and phosphate, in the presence of a variety enzymes

Answer 7

Matrix vesicle mediated mieralization

Question 8

Two stage of mineral crystal formation

Answer 8

1. Formation of small embryo crystals
2. Crystal growth, characterized by the deposition of calcium and phosphate onto the crystal surface

Question 9

Promoted on crystaline material having similar lattice spacings,

Answer 9

Crystal growth

Question 10

Odontoblasts actively transport calcium ions to the mineralization site via?

Answer 10

Active transport through the cell

Question 11

This mineralization actively controls the level of calcium

Answer 11

Mineralization of circumpulpal dentin

Question 12

Deposition of calcium occurs on the?

Answer 12

Template formed by type 1 collagen

Question 13

Mineral crystal deposition occurs at the?

Answer 13

Gap zone within the collagen fibrils

Question 14

A pool of. ___, ___ and ___ is secreted aqt the mineralization front and is transported iontracellulary along the odontblast process

Answer 14

Chondroitin sulphate, decorin and biglycan

Question 15

A pool that is associated with guiding mineral deposition

Answer 15

Chondroitin sulphate pool

Question 16

CS may be involved in?

Answer 16

Transport of calcium and phosphate to gap zones in the collagen

Question 17

This dentin-pecific protein is secreted at the mineralizing front and is highly acidic

Answer 17

Dentin phosphoprotein

Question 18

A phosphorlyated protein capable of promoting mineralization

Answer 18

Osteopontin

Question 19

Been shown to inhibit growth of hydroxyapatite while promoting the binding of calcium and phosphate to collagen

Answer 19

Osteonectin

Question 20

Found in soft tissues and body fluids and ctively inhibits mineralization

Answer 20

Pyrophosphate

Question 21

In what part of the tissue does pyrophosphate degrades and pyrophosphate present, allowing mineralization to occur

Answer 21

Hard tissues

Question 22

The first formed root dentine

Answer 22

Hyaline layer

Question 23

Initial process of bone and dentine mineralization

Answer 23

Matrix vesicle mediated minealization

Question 24

Ions that are required for mineralizatoin

Answer 24

Calcium and phosphate

Question 25

Mineralization of osteoid requires remodeling of the original tissue matrix to remove inhibitory __

Answer 25

Proteoglycans

Question 26

Contains a collagenous matrix rich in dermatan suplhate, proteoglycans and versican

Answer 26

Osteoid

Question 27

Tissue specific proteins that influences the mineralization in a similar manner to that seen in dentin mineralizatio

Answer 27

Osteopontin, osteocalcin and bone sialoprotein

Question 28

Sole mineralization mechanism of enamel

Answer 28

Heterogenous mineralization

Question 29

Enamel specific proteins that is important in nucleation and regulatioon of mineralization

Answer 29

Amelogenins and non-amelogenins

Question 30

Role of non-amelogenins

Answer 30

Acts as seeding/epitactic sites for initial crystal deposition

Question 31

role of amelogenins

Answer 31

Provde regulation by inhibiting crystal growth

Question 32

Mineralization of cementum in the first formed cementum

Answer 32

Heterogenous