Midterms_Multiple Sclerosis Flashcards
a chronic, progressive, non-
contagious, degenerative disease of the CNS
characterized by demyelination of the neurons.
Multiple Sclerosis
.This is described as the ________ of the
brain, spinal cord, and optic nerve’s white matter
and usually occurs as small patches
demyelination
what age does MS usual happen?
20 and 40
Causes disruption of electrical messages from
the brain to the peripheral nervous system.
_____________ findings are abnormal
Electroencephalogram
A lumbar puncture indicates ______
increased gamma
globulin, but the serum globulin level is
normal.
Other possible factors:
(may help destroy axons and myelin sheath)
A. trauma
B. Anorexia
C. toxins
D. Nutritional deficiencies
E. Vascular lesions -
F. Anorexia nervosa
More prevalent in the _____
Northern latitudes and
among Caucasians
defined as damage to the
myelin, the protein, and lipid-rich substance that
serves as a cover to the neural fibers of the
brain spinal cord.
Demyelination
Due to demyelination, there is a disruption in the
_______the affected nerve fibers are scarred because of the inflammatory reactions.-
nerve transmissions,
This is described as the demylination of the
________,_______, _________
and usually occurs as small patches
brain, spinal cord, and optic nerve’s white matter
Results in disordered transmission of nerve impulses Inflammatory changes lead to the scarring of the affected nerve fibers.
Demyelination
Signs and Symptoms of MS
(BUV DMS IV)
Body weakness and fatigue
● Unusual reflexes, either hyperactive or absent
● Visual disorders may be nystagmus ( impaired
double vision)
● Dysarthria and dysphagia
● Motor disturbances (incoordination and tremor)
● Sensory dysfunctions (paresthesias, impaired
sense of position and vibration, reduced deep
sensation)•
● Impaired urinary functions (frequency,
incontinence,hesitancy, retention, urgency) •
● Behavioral patterns ( depression, emotional
lability,disturbed cognition)
Diagnostic test for MS
Cerebrospinal fluid (CSF) analysis
Cerebrospinal fluid (CSF) analysis reveals…
elevated protein level,increased white blood cells.
Electrophoresis of CSF shows
increased myelin basic protein and IgG bands.
Supporting Diagnostic Tests Include
electroencephalography, evoked potential studies, computed tomography (CT) scan, and magnetic resonance imaging(MRI)