Midterm - Lecture Flashcards
What parts of the sarcomere stay the same during contraction?
Width of A band and lengths of thin filaments do not change
What are the different types of muscle contraction
IsoTONIC - Tone is the same, Tension is constant but muscle changes length
- Concentric Isotonic - muscle shortens during a contraction (lifting weight)
- Essentric Isotonic Contraction - muscle lengths during contraction (slowly controlling down)
IsoMETRIC - Tension without changing the muslce length, important for posture, example - plank
What are the sequence of events in the contraction cycle of a muscle?
- Sarcoplasmic reticulum releases Ca2+ into sarcoplasm
- Ca2+ binds to troponin
- Troponin moves tropomyosin away from myosin-binding site on actin
- Contraction Cycle can begin
- ATP Hydrolysis
- Attachment of myosin to actin
- Power stroke
- Detachment of myosin from actin
Which type of ATP production do we do first? Which one is most efficient?
Creatine phosphate - first source of energy when muscle contraction occurs
Aerobic respiration is the most efficient, yields the most ATP
What are the layers and roles of the connective tissue in muscles?
Epimysium - Dense Irregular Conncective tissue that forms the outer layer around the entire muscle (Not present in cardiac muscle)
Perimysium - Dense Irregular Connective tissue that groups the 10-100 muscles fibers into fascicles
Endomysium - Reticular fibers, Separate the individual muscle fibers from one another
What determines the strenth of a contraction?
Size of the motor units and number of units activated at any given time
What are the four curves of the vertebral column?
Cervical Lordosis Thoracic Kyphosis Lumbar Lordosis Sacral Kyphosis Lordosis - arch
What is the AOIN for the Quadratus Lumborum?
Action: Unilaterally: Laterally Flex the Vertebral Column Tilt the Pelvis Laterally Assist to Extend the Vertebral Column Bilaterally: Fix the last rib during forced inhallation / Exhallation Origin: Posterio Iliac Crest Insertion: Last Rib and Trasverse Process of L1-L4 Nerve: Branch of T12 and L1 (Lumbar Plexus)
What are the types of ATP production within muscle cells?
Creatine phosphate
Aerobic Respiration - oxygen
Anaerobic Respiration - pyruvate / lactic acide
What parts of the sarcomere can disappear during maxiumal contraction?
I Band and H Zones can disappear during maximal contraction
In epidermal wound healing, what is the main cell involved?
Basal cells
What controls the force of contraction / tension produced in a muscle fiber?
Frequency of stimulation (#impulses/second at NMJ)
Number of fibers stimulated
What is the sequence of healing in deep wounds?
*I Might Puke Monday* Inflammation (Prep for repair) Migratory (Network) Proliferation (Fill in the gaps) Maturation (Reorganization)
What are the muscle groups for inspiration and expiration?
Primary -
- Diaphragm
Accessory -
- Intercostals External (Inhalation) / Internal (Exhalation)
- Serratus Superior (Inhalation) / Inferior (Exhalation)
- Scalene, Sternocleidomastoid
- Quadratus Lomborum (Fix the last rib during forced inhalation/exhalation)
What is acetylcholine and what is its function in the body?
Acetylcholine is a neurotransmitter that is released at the Neuromuscular junction and forms the bridge between a nerve action potential and triggers a muscle action potential
What are the Ligaments of the spine?
Anterior Longitudinal Ligament - primary spine stabilizer, thickest prevents Hyperextention
Posterior Logitudinal Ligament - primary spine stabilizer
Ligumentum Nuchae - Occipital Protuberance to spinous process of C7
Supraspinous Ligament - Extends from LN to spinus process of thorocolumbar vertebrae
Interspinous
Nuchal Ligament
Transverse Ligaments
What is the order of skin layers, which layer(s) only exist in thick (hairless) skin?
*BattleStar Gallactical Love Child* Stratum Basale Stratum Spinosum Stratum Granulosum Stratum Lucidum (clear, only in thick) Stratum Corneum
What are the types of synovial joints and their movements?
Plane, Hinge, Pivot, Condyloid, Saddle, Ball & Socket
Gliding, Angular, Rotation, Special Mvmts
What is the structure of an intervertebral disc (IV)
Anulus Fibrosus - the outer, fibrous, thick layer (thicker in the front - more likely to ‘slip’ to the back
Nucleus Pulposus - inner gelatinus spongy mass / cushion
What is the Phrenic Nerve, what does it innervate and why is it important?
The Phrenic Nerve innervates the Diaphragm - if it is injured / severed (C3,4,5), then the person can no longer breathe on their own
What are the key differences between epithelial and connective tissue?
Epithelial: Many cells packed tightly together Little to no extra cellular matrix No blood vessels Almost always forms surface layers Almost always adjacent to connective tissue
Connective:
Widely Scattered Cells (Blood)
Large amount of extracellular material
Significant networks of blood vessels
What are the 4 main tissue types?
epithelial, connective, muscular, nervous