MIDTERM Integumentary Flashcards
Give the 5 functions of the Skin
- Resistance to trauma and infection
- Other barrier functions
- Vitamin D synthesis
- Sensation
- Thermoregulation
an epithelial tissue in the form of keratinized stratified squamous epithelium
Epidermis
a connective tissue layer in the form of dense fibrous irregular connective tissue
Dermis
loose connective tissue containing fat or adipose tissue
Hypodermis or subcutaneous
3 layers of the skin
- Epidermis
- Dermis
- Hypodermis or subcutaneous
Epithelial tissue which is composed of 4 different types of cells:
- Keratinocytes
- Melanocytes
- Langerhans cells / dendritic cells
- Merkel cells
most numerous and most prominent; these cells that are transformed into keratin
Keratinocytes
produce skin pigment or skin color
Melanocytes
defense cells; antigen-presenting cells (APC)
Langerhans cells / dendritic cells
for tactile/touch sensation
Merkel cell
The keratinocytes form five distinct layers of the epidermis:
- stratum basale / germinativum
- stratum spinosum.
- stratum granulosum / granular layer
- stratum lucidum / clear cell layer
- stratum corneum.
consists of 15 - 20 layers of flattened keratinized cells- cytoplasm is filled with keratin; surface cells continuously shed off
Stratum Corneum
seen only in thick skin; flattened clear cells devoid of nuclei and organelles
Stratum Lucidum / clear cell layer
3-5 layers of flattened polygonal cells whose cytoplasm is filled with darkly basophilic granules called keratohyaline granules
Stratum Granulosum / granular layer
single layer of columnar or cuboidal cells which undergo intense mitosis for constant production of epidermal cells
Stratum Basale / germinativum