MIDTERM II Flashcards
after centrifuge what percentage contains components immune function?
buffy coat
what percentage of the blood is plasma?
55%
functions of blood
transport, regulation, protection
erithrocytes are filled with?
hemoglobin (97%) for gas transport
There are no mitochondria in
RBCs
which is present in a mature red blood cell
Plasma Membrane
The pigment in a Hemoglobin that gives it its’ red color is called what?
Heme- it has an iron atom
each hemoglobin molecule can transport how many oxygen molecules
4
oxygen binds to which portion of the hemoglobin
iron atom
what is hematopoiesis
blood cell formation in the red bone marrow
hematopoietic stem cells do what?
give rise to all formed elements of hematopoiesis
What is erythropoiesis
Production of red blood cells
a hematopoeitic stem cell will give rise to
all of the above
what response would you expect after traveling to high altitude for 2 weeks
kidneys would secrete extra erythropoeitin
target organ of erythroproeitin?
red bone marrow
Causes of anemia
Blood loss, low RBC, high RBC
an elevated neutrophil count would mean
an acute bacterial infection
antihistamines counter the actions of which WBCs
Basophils
the immediate response to blood vessel damage
vascular spasm
why dont plateletes form plugs in undamaged vessels
only platelets contacted with exposed collagen fibers and von willebrand factor causes them to be sticky and form plugs
Humoral stimuli
When changing blood levels of ions and nutrients directly stimulate secretion of hormones
Neural stimuli
When a nerve fiber stimulates hormone release(sympathetic nervous system)
Hormonal stimuli
When hormones stimulate other endocrine organs to release their hormones(i.e. hypothalamus)
when the ovaries secrete estrogen this is an example of
hormonal stimulation
when pancreas releases insulin it is an example of
humoral stimulation
permissiveness
one hormone cannot exert effects without another hormone being present
synergism
more than one hormone produces the same effect- amplification
antagonism
one or more hormones opposes the action of another hormone
two major lobes of the pituitary gland
posterior(neural) and anterior (glandular)
what does the infindibulim do?
it is the point of attachment between hypothalamus and pituitary gland
what kind of organ is the hypothalamus
neuroendocrine
what two hormones are secreted and stored by the posterior pituitary gland
oxytocin and ADH
where are oxytocin and ADH synthesized?
in the hypothalamus
does the anterior lobe of the pituitary gland have a direct neural connection to the hypothalamus?
NO-it is a vascular connection
the anterior lobe of the PG carries….
releasing and inhibiting hormones that regulate hormone secretion
What is Oxytocin
Strong stimulant of uterine contractions, pregnant chicks
The Growth Hormone(GH)
a tissue building hormone that increases blood levels of fatty acids and stimulates protein synthesis…conserves glucose, breaks down glycogen
What are tropic hormones?
hormones that act on other endocrine glands and cause them to release their hormones
The tropic hormones are?
FSH,LH, ACTH, TSH (FLAT)
The direct hormones are?
Prolactin, Endorphines, Growth H, (PEG)
Hypersecretion of GH in children
results in gigantism
Hypersecretion of GH in adults
will not change growth(acromegaly) may change facial structure
hyposecretion in children
will result in pituitary dwarfism
thyroid stimulating hormone does what?
stimulates normal developement and activity of the thyroid, inhibited by rising blood levels
adrenocorticotropic hormone does what?
stimulates adrenal cortex to release corticosteroids(help body resist stress)
two gonadotropins are?
FSH-stimulates egg or sperm
LH- promotes production of testosterone and estrogen
prolactin (PRL)
stimulates milk production
cortical nephrons
shorter loops
juxtamedullary nephrons
are next to the medullar junction
nephron capillary bed flow
afferent arteriole- glomerulus-efferent arteriole
why is blood pressure in glomerulus high
because the afferent arteriole has a larger diameter than the efferent
which blood vessel is associated with the nephron
efferent arteriole
which type of nephron plays an important role in producing concentrated urine
juxtamedullary nephrons
which would not be found in a normal filtrate
albumin
most of the nutrients in the filtrate are reabsorbed where?
proximal convoluted tubule
The distal convoluted tubule and collecting duct do what
vary reabsorption with the body’s needs, this is fine tuned by hormones
The proximal convoluted tubule is
the main site of secretion and reabsorption
When is it called urine and not filtrate
once it leaves the connecting duct
the urine forming units of the kidney are
nephrons
podocytes are part of
filtration slits
which of the following factors contributes to the higher filtration rate in the glomuler capillaries compared to other capillary beds
all of the above
drinking too much alcohol results in a headache because?
alcohol inhibits ADH secretion