Midterm

Question 1

What are the normal physiological changes in bone density?

Answer 1

Destructive (resorptive): Ageing, Disuse Atropy

Question 2

What are the abnormal pathological changes in bone density?

Answer 2

Decreased - osteoclastic - lytic - destructive
Increased - osteoblastic - sclerotic - productive
Mixed

Question 3

What can cause a generalized bone tissue destruction pattern?

Answer 3

Serum Ca2+ levels
Nutritional Dz
Disuse atrophy

Question 4

What can cause a localized lesion of bone tissue destruction?

Answer 4

Tumor

Infection

Question 5

What type of bone destructive pattern will metabolic dz give you? What dz’s?

Answer 5

Generalized
Abnormal serum Ca2+ levels
2-renal/nutritional-HPT = osteopenia

Question 6

What will you see on rads w/ disuse atrophy?

Answer 6

Thin cortices & reduced bone density

Question 7

Bone tissue distruction from a localized region can be seen when on x-ray? What may be a better modality?

Answer 7

7-10 days after insult
30-60% of mineral content lost to visualized
Scintigraphy may show sooner

Question 8

What is this destructive pattern?

Answer 8

local monostotic