Midterm 2 Flashcards
(88 cards)
Define character
An observable, physical, heritable factor that varies among individuals (hair color, height)
Define trait
The alternative forms of a character (brown/black hair)
Define true-breeding
Organisms that “breed true” with respect to a particular trait - breeding within only gives rise to offspring with that trait.
*Self-pollination would produce progeny that all have the same phenotype as the parent. e.g. If a plant variety was true breeding for a dominant train, all progengy would have dominant trait
What is the law of segregation?
Two alleles for a heritable character separate from each other during meiosis and end up in different gametes.
What is a test-cross?
A cross between a dominant phenotype (S?) and a homozygous recessive (ss).
What is the law of independent assortment?
Alleles for different traits assort independently of each other during Meiosis

Why did Mendel use pea plants?
- It’s easy to control mating in peas
- Peas have many easily-scored,
true-breeding, heritable traits
- Relatively short
generation times (one year), so
many experiments could be performed
- Peas make lots of offspring
Define qualitative variation
Either-or of alternative traits (red or pink)
Define quantitative variation
Many genes affect a trait and there are alleles at different loci.
Ex. Human height affect by alleles at 180 loci
Define evolution
Changes in allele frequencies in populations over time
Define population
A group of same species organism living in the same area at the same time. Interbreeding occurring
What process forms new alleles?
Mutation
What is a point mutation?
Substitutions of a single base in a gene. There can either be a protein change at higher levels or no protein change (silent point mutation).
What is an insertion/deletion mutation?
Addition/loss of one or more bases.
- Multiple of 3 bases results in loss of amino acid
- Non-multiple of 3 results in ALL amino acids changing (frame-shift)

What is a frame-shift mutation?
When a non-multiple of 3 amount of bases are inserted/deleted resulting in a change of ALL amino acids in that gene.

What is gene duplication?

What organisms are more susceptible to mutations?
Organisms with rapid generations times (divide frequently)
How does a mutation affect the phenotype of an organism?
Mostly negative
Sometimes neutral but RARELY positive
Are mutations goal directed?
No they arise randomly
How do mutation and sexual reproduction generate variation?
Mutation makes new alleles
Sexual reproduction shuffles alleles
A diploid organism can have at most how many different alleles at a particular locus?
2
Define gene pool
The sum of all copies of all alleles at all loci in a population.
What does it mean if a population is monomorphic or fixed at a particular loci?
There is only one allele at this locus
What are the 5 conditions for the Hardy-Weinberg Equilibrium?
- No mutation
- No gene flow
- Large population size
- No natural selection
- Mating is random









