Midterm 1 Flashcards
Brain
- “tissue within the skull’
- produces & is affected by behavior
organ of soft nervous tissue that functions as coordinating centre of sensation & intellectual activity
Behavior
obserable phenomenon produced by NS that has both a cause & function
Behavior & Brain→ Nature vs. Nurture?
not reducible to being simply result of nature vs nurture
- affected by BOTH
- affect each other
- inextricably linked
Perspectives on Brain & Behavior (3)
1) Mentalism
2) Dualism
3) Materialism
1) Mentalism
* who?
Aristotle
- explanation of behavior as function of nonmaterial mind
- mind (“soul/psyche”) found in heart & departed from body after death
- brain cooled blood
2) Dualism
- who?
- behavior produced by?
- location
Rene Descartes
- 2 entities (nonmaterial mind & material body) contribute to behavior
-
mind directs rational behavior (through brain)
- in pineal gland beside ventricles
- regulates behavior/movement by directing flow of ventricular fluid to muscles
-
body/brain direct all other behaviors via mechanical & physical principles
- sensation, movement digestion
-
mind directs rational behavior (through brain)
- influenced by mechanical devices of the time (hydraulics)
Dualism - Problems with Descartes Theory (3)
1) Mind-Body Problem
2) Pineal gland involved in biological rhythms but NOT intelligence or behavioral control
3) fluid is NOT pumped from ventricles to control movement
Mind-Body Problem
how does a non-material mind & physical brain/body interact?
3) Materialism
* supporting evidence?
behavior explained as function of NS without explanatory recourse to mind
- EVIDENCE: case studies → people with brain damage indicate that brain controls behavior & produces mind
NO nonmaterial mind
- mind has physical basis → BRAIN
Phineas Gage → significance?
story shows that changes to brain can change behavior
Evolution of Evolution
- who?
Alfred Wallace & Charles Darwin struck by the many similarities (physical atrributes & behavior) among species
- questioned how species could be so different yet similar at the same time
- lead Darwin to propose his theory of Natural Selection
Darwin’s Theory of Natural Selection
- involves?
- how?
involves gradual change in frequency that a gene is expressed within a population
- occurs over many generations
- organisms with advantageous traits for given environment are able to survive & procreate
Epigenetics
study of differences in gene expression related to environment & experience
How are traits naturally selected?
source of variability (i.e. genetic mutation)
→ adaptive trait → ↑ chance of survival → trait passed on to offspring
Implications of Natural Selection for study of brain/behavior (3)
1) Brain/neurons are related
2) behaviors are related
3) complexity in brain & behavior evolved gradually, in response to environmental demands & experience
1) Brain/neurons are related
enables animal models for studying structures & functions
- because all animal species are related, so too must their brains
2) behaviors are related
enables animal models for studying behaviors
- all species of animals are related, so too must their behavior
Why study Brain & Behavior? (3)
1) how brain produces behavior is major unanswered scientific question
2) many behavioral disorders can be explained & potentially cured by understanding brain
3) brain = most complex living organ on Earth
1) how brain produces behavior is major unanswered scientific question
study brain for purpose of understanding humanity
understanding brain function allows improvements in many aspects of our world (educational/economic/social systems)
2) many behavioral disorders can be explained & potentially cured by understanding brain
2000+ disorders are related in some way to brain abnormalities
Anterior
frontal
rostral
Posterior
caudal
back
Dorsal
superior
above
Ventral
Inferior
below
Medial
middle
Lateral
side
Dorsal side
spinal cord vs. brain
spinal cord: back
- think animal on all fours
brain: top of head
(3) Planes
1) Horizontal
2) Sagittal
3) Coronal
1) Horizontal
aka Axial/Transverse
- divides body into superior & inferior parts
2) Sagittal
* (2) types
vertical plane passing from anterior to posterior, dividing body into right & left halves
a) mid-sagittal: sagittal plane through midline
b) parasagittal: any plane parallel to sagittal plane
3) Coronal Plane
any vertical plane that divides body into dorsal & ventral sections
Contralateral vs. Ipsilateral
In reference to pathways within the body
- Contralateral = situated on/coordinated with opposite side of body
- Ispilateral = belonging to/occurring on same side of the body
Afferent vs. Efferent
Afferent = incoming info (sensory) into CNS
Efferent = outgoing info leaving CNS
NERVOUS SYSTEM
- Afferent nerves
sensory pathways
- nerve impulses conducting from receptors/sense organs towards CNS
- dendrites pick up sensory stimuli
NERVOUS SYSTEM
- Efferent nerves
motor pathways
- conduct nerve impulses away from CNS to effector organs
- axons receive impulse from cell body
Interneurons
- located in CNS
- connect sensory & motor neurons
- play role in reflex arc
- allow quicker responses without involving brain
Primary Functions of the Brain (3)
1) Create a sensory reality
2) Store & integrate information
3) Produce behavioral response in response to information
PRIMARY FUNCTIONS OF THE BRAIN:
1) Create a sensory reality
- varies across species
- more acute/sensitive senses (i.e. dogs)
- varies across individuals
- i.e. rods/cones (color blind)
Nervous System
- made up of? (3)
- functions?
1) Brain
2) Spinal Cord
3) Nerves
- recieves information (via nerves)
- interprets information (via brain)
- generates responses to information (through spinal cord to effector organs)
Nervous System
- divided into (2) main parts
1) CNS
2) PNS
CNS
- functions?
- (2) parts
-
recieves, processes, interprets, stores & responds to sensory information
1) Brain
2) Spinal cord - bridge b/w brain & peripheral nerves
2) Spinal Cord
* definition
collection of neurons & supportive tissue running from base of brain down center of back
- protected by spinal column
2) Spinal Cord
* injury
INJURY leads to paralysis
- Quadriplegia
- Paraplegia
Quadriplegia
partial/total inability to move all four limbs
- caused by damage to cervical spinal cord segments (C1-C6)
Paraplegia
partial/total inability to move lower limbs
- caused by damage to thoracic, lumbar or sacral region of spinal cord
2) Spinal Cord
* roles
- role in voluntary movement & automatic functions
- carries sensory info to brain
- carries motor commands from brain
- controls spinal reflex
Spinal Cord → Spinal REFLEX
automatic response to sensory information that is independant of brain
- sensation at side relayed to neurons in spinal cord via sensory pathway
- spinal cord returns signal along motor pathway causing “reflex”
- signal is also sent to brain, alerting it to sensation & response
Example of Spinal Reflex
- describe
Patellar Reflex
- stimuli (tap below knee) → AP in muscle spindle within quad
- travels to spinal cord via sensory neuron → Glu release @ synapse
- motor neuron activated → quadricep contraction (extension)
-
interneuron activated → inhibitory Glycine release → inhibit antagonist muscles causes hamstring relaxation
- detect info, determines which muscle to contract & stimulates motor response (coordinate reflex)
Interneuron role in Spinal Reflexes
integration of motor commands & sensory feedback signals is used to control muscle activity during movement
- coordinate reflex
Spinal Cord Regions (5)
- Cervical (C1-C6)
- Thoracic (T1-T12)
- Lumbar (L1-L5)
- Sacral (S1-S5)
- Coccygeal
PNS
- functions
- divided into (2) main systems
- provides information to CNS
- provided with response information from CNS
1) Somatic NS
2) Autonomic NS
1) Somatic NS
consists of spinal & cranial nerves
- sensory info from receptors in skin/muscles/joints/sense organs recieved by sensory nerves & sent to CNS
- motor nerves carry messages from CNS to skeletal muscles to produce movement
Cranial Nerves
- 12 pairs
- monitored by brain
- sensory, motor or mixed (both)
- supply:
- sense organs
- face & head muscles
4 involved in Parasympathetic Division of ANS
- oculomotor, facial, glossopharyngeal, vagus
- many are attached at brainstem region
Cranial Nerves (12)
- Olfactory
- Optic
- Oculomotor
- Trochlear
- Trigeminal
- Abducens
- Facial
- Auditory Vestibular
- Glossopharyngeal
- Vagus
- Spinal Accessory
- Hypoglossal
Olfactory
1
smell
sensory
Optic
2
sensory
vision
Oculomotor
3
motor
eye movement
Trochlear
4
motor
eye movement
Trigeminal
5
mixed
masticatory movements & facial sensations
Abducens
6
Motor
eye movement
Facial
7
mixed
facial movement & sensation
Auditory Vestibular
8
sensory
hearing & balance
Glossopharyngeal
9
mixed
tongue & pharynx movement & sensation
Vagus
10
mixed
- sensory info about heart, BV, viscera
- movement of larynx & pharynx
Spinal Accessory
11
motor
neck muscles
Hypoglossal
12
motor
tongue muscles
Mnemonic to remember:
a) Cranial Nerves
b) sensory/motor/mixed
a) Oh Oh Oh Tiny Tits Are Fun And Give Virgins Awkward Hips
b) Some Say Marry Money But My Brother Says Big Brains Matter Most
Spinal Nerves
monitored by spinal cord
- each contains both sensory & motor fibers
- supplies a single dermatome
DERMATOME
region of body that corresponds to particular spinal nerve that it is innervated by
area of skin supplied by a particular spinal nerve
Law of Bell & Magendie
Sensory fibers → dorsal side of spinal cord (→ CNS)
Motor fibers → ventral side of spinal cord (→ body)
Spinal Nerves
- Ventral vs. Dorsal Fibers
Ventral Fibers
- carry info from spinal cord → muscles
Dorsal Fibers
- carry info from body → spinal cord
PNS → Autonomic Nervous System
- regulates glands, BV & internal organs
- internal environment
- involuntary
- comprised of (2) independant systems:
- Sympathetic NS
- Parasympathetic NS
Sympathetic NS
- location
- functions
Innervates @ thoracic & lumbar level of spinal cord
→ STIMULATORY
- arouses body during times of stress
- sexual arousal
- initiates fight or flight response
ANS → Parasympathetic NS
→ INHIBITORY
- allows body to rest & digest
-
4 cranial nerves & spinal nerves @ sacral level
- ocolumotor (III)
- facial (VII)
- glossopharyngeal (IX)
- vagus (X)
Parasympathetic Function of 4 Cranial Nerves involved in ANS
Oculomotor (III) → contracts pupils
Facial (VII) → salivation
Glossopharyngeal (IX) → salivation
Vagus (X) → slows heartbeat, constricts airways, digestion, stimulates bladder & erection
Effect of Sympathetic NS on…
1) pupils
2) salivation
3) airways
4) heartbeat
5) digestion
6) glucose release
7) bladder
8) genitals
1) dilates
2) inhibits ↓
3) relaxes
4) accelerates ↑
5) inhibits ↓
6) stimulates ↑
7) contracts
8) stimulates ejaculation
Effect of Parasympathetic NS on…
1) pupils
2) salivation
3) airways
4) heartbeat
5) digestion
6) glucose release
7) bladder
8) genitals
1) contracts
2) stimulates
3) constricts
4) slows ↓
5) stimulates ↑
6) ↓
7) stimulates ↑
8) stimulates erection
Brain
- Surface Features
Meninges - tough triple-layered protective covering
- dura mater
- arachnoid layer
→subarachnoid space (filled with CSF)
- pia mater
Meninges
(1) Dura Mater
“hard mother”
- tough double layer of fibrous tissue enclosing brain & spinal cord in loose sac
Meninges
(2) Arachnoid Layer
thin sheet of delicate CT
web-like fibers extend into subarachnoid space & attach to pia mater
Meninges
(3) Pia Mater
“soft mother”
delicate inner membrane of CT fibers that adheres to brain’s surface
- thin, translucent
- contains capillaries
Subarachnoid Space
space between arachnoid layer & pia mater
- filled with cerebrospinal fluid to cushion brain
Cerebrospinal Fluid
- functions (2)
clear solution of NaCl that fills ventricles
- circulates around brain & spinal cord in subarachnoid space
- cushions brain
- transports substances in/out of brain (waste/nutrients)
Cerebral Cortex
thin folded film of nervous tissue that forms outer layer of forebrain
(3) parts of cerebral cortex
1) Gyri
2) Sulci
3) Fissures
1) Gyri
bumps/ridges in brain’s folded surface (cerebral cortex)
2) Sulci
depressions/grooves in cerebral cortex surrounding gyrus
- usually found in neocortex or cerebellum
3) Fissures
large furrow that divides brain into lobes & hemispheres
Major Fissures (3)
1) Central
2) Longitudinal
3) Lateral (Sylvian)
Fissures →
1) Central
seperates frontal & parietal lobe
Fissures →
2) Longitudinal
seperates left & right hemispheres
Fissures →
3) Lateral (Sylvian)
seperates frontal & parietal lobe from temporal lobe
BRAIN → Major Surface Structures
1) 4 Lobes
a. occipital
b. parietal
c. temporal
d. frontal
2) cerebellum
3) brainstem
4) cranial nerves
LABEL DIAGRAMS OF BRAIN
Views:
Lateral
Medial
Ventral
Dorsal
Brain → Internal Features
1) White Matter
2) Gray Matter
3) Ventricles
1) White Matter
areas of NS rich in fat-sheathed neural axons (myelin)
- arranged in dorsal & ventral tracts
- form connections between brain cells
2) Gray Matter
areas of NS mostly composed of cell bodies & capillary blood vessels
- function to collect /modify info or support this activity
3) Ventricles
cavities in brain that produce & contain CSF that cushions brain & plays role in brain metabolism
Ventricular System (4)
CSF flow:
- lateral ventricles
- third ventricle
- fourth ventricle
→ cerebral aqueduct (canal running length of spinal cord)
Lateral Ventricles
paired, one in each hemisphere
extend laterally in cerebrum
Third Ventricle
at midsagittal line between lateral ventricles
- between thalami in diencephalon
Fourth ventricle
between cerebellum & brainstem
Functions of Ventricles (2)
1) role in brain metabolism
2) cushions brain (protection)
Corpus Callosum
band of white matter fibers connecting left & right hemisphere to allow communication between them
Principal Structures of CNS
1) Spinal Cord
2) Brainstem
3) Forebrain

frontal
parietal
temporal
occipital
brainstem
cerebellum
(2) main types of cells in the Brain
1) Neurons - carry out brain’s major function
2) Glial Cells - aid/modulate neuron’s activities
Principle of Levels of Function
- replicated function
- add new skills
- increase brain size & behavioral complexity
Principle of Levels of Function
- replicated function
- add new skills
- increase brain size & behavioral complexity
EXPLAIN
brain has evolved functional levels that overlap in purpose & allow for growing complexity of behavior
- newer levels partly replication functions of older ones
- each new level of training adds new abilities that overlap build on previously acquired skills
Brainstem
central structures of brain
- extends upward from where spinal cord enters brain & into lower areas of forebrain
- controls movement
- creates basic sensory reality
- responsible for most unconscious behavior
Brainstem
- (3) parts
1) Hindbrain - top (forearm)
2) Midbrain - middle (wrist)
3) Diencephalon - lowest (fist)
Brainstem > HINDBRAIN
- composed of? (4)
1) Medulla Oblongata
2) Pons
3) Cerebellum
4) Reticular Formation
BRAINSTEM > Hindbrain
1) Medulla Oblongata
continuation of spinal cord in skull
- vital functions
- contains control centres for heart & lungs
- regulates breathing & CV system
- gag reflex
- damage = DEATH
Brainstem > HINDBRAIN
2) Pons
- location
- functions
between midbrain (above) & medulla oblongata (below) & in front of cerebellum
- bridge
- nuclei within recieve inputs from cerebellum & form bridge to rest of brain
Brainstem > Hindbrain
3) Cerebellum
under cerebral hemispheres
- motor coordination (timing/rhythm/dexterity)
-
cognitive functions
- involved in basic procedural memory
- vital for conditioning (association b/w stimuli & intended motor response)
Brainstem > HINDBRAIN
4) Reticular Formation
extends length of brainstem at core
- netlike mixture of neurons (gray matter) & nerve fibers (white matter)
- nuclei localized along length into small patches
- each has special function in stimulating forebrain
- Reticular Activating System (RAS)
Reticular Activating System (RAS)
responsible for regulating arousal/wakefulness & sleep-wake transitions
- helps mediate transitions from relaxed wakefulness to attentive state
Brainstem > Midbrain
- parts (2)
1) Tectum
2) Tegmentum
Brainstem > Midbrain
1) Tectum
- composed of? (2)
4 bumps on posterior region located dorsally
-
sensory component of midbrain
- recieves sensory info from eyes & ears
1) Superior Colliculi
2) Inferior Colliculi
Brainstem > Midbrain
1) Tectum
* Functions of Colliculi
-
sensory-motor coordination
- process sensory info
- produce orienting movements related to sensory inputs
- used for reflexive orienting
i.e. automatically turn to look at source of sound
Brainstem > Midbrain
1) Tectum
a. Superior Colliculi
VISUAL
- recieves large bundle of nerve fibers from optic nerve
Brainstem > Midbrain
1) Tectum
a. Inferior Colliculi
AUDITORY
- recieves input from auditory pathways
Brainstem > Midbrain
2) Tegmentum
anterior region ventral to tectum
- composed of many nuclei
- involved in sensation & movement-related functions
- perception of pain
Brainstem > Midbrain
2) Tegmentum
* composed of? (3)
1) Red Nucleus
2) Substantia Nigra
3) Periaqueductal Gray Matter
Brainstem > Midbrain
Tegmentum
1) Red Nucleus
- location & function
controls limb movements
- coordination/control
paired nuclei between substantia nigra & reticular formation
Brainstem > Midbrain
Tegmentum
2) Substantia Nigra
- damage/destruction causes?
connected to forebrain
- dark colour due to dopamine
- many effects mediated by striatum
- allows basal ganglia to function normally
Symptoms of Parkinson’s Disease related to destruction of substantia nigra
Brainstem > Midbrain
Tegmentum
3) Periaqueductal Gray Matter
made up of cell bodies that surrounds aqueduct that joins 3rd & 4th ventricles
- contains circuits controlling species-typical behavior
- important role in modulation of pain by opioid drugs
- contains receptors for endogenous cabinoids (i.e. morphine/marijuana)
Brainstem > Diencephalon
integrates sensory & motor info on its way to cerebral cortex
Brainstem > Diencephalon
- principal structures (2)
1) Hypothalamus
2) Thalamus
Brainstem > Diencephalon
1) Hypothalamus
paired structure inferior & anterior to thalamus
Mediates autonomic functions/responses & hormones
- controls hormone production with pituitary gland
- eating/drinking, sexual behavior, temperature regulation, emotional behavior & sleeping
Brainstem > Diencephalon
3) Thalamus
sensory & motor gateway
- recieves inputs from all sensory systems → integration & relay to appropriate cortical region
- <em>i.e. optic tract send info to lateral geniculate nucleus, which sends processes & sends it to visual region of cortex in each hemisphere </em>
Principal Structures of Brain:
3) Forebrain
* composed of? (3)
-
largest region of mammalian brain
1) Neocortex (Cerebral cortex)
2) Limbic System
3) Basal Ganglia
Forebrain
1) Basal Ganglia
- location & function
- collection of nuclei below white matter of cortex
- connected to thalamus & midbrain
- control/coordination of voluntary movement (NOT PRODUCE) with thalamus, substantia nigra & subthalamic nucleus
- force/exertion
Forebrain
1) Basal Ganglia
* principal structures? (3)
1) Caudate nucleus
2) Putamen
3) Globus Pallidus
Forebrain > Basal Ganglia
1) Caudate nucleus
* location
tail
paired structure
forms dorsal striatum with putamen
- near midline, above thalamus & directly below lateral ventricles
Forebrain > Basal Ganglia
2) Putamen
round structure at base of forebrain
- regulates movement & influences types of learning
Forebrain > Basal Ganglia
3) Globus Pallidus
paired structure medial to putamen
- internal & external portion
- pale appearance due to numerous myelinated axons
- recieves input from caudate & putamen (striatum) & routed to thalamus
-
inhibitory output
- DIRECTLY → by globus pallidus interna
- INDIRECTLY → globus pallidus externa passes info to interna
-
inhibitory output
Forebrain > Basal Ganglia
- Dysfunction/Disease/Disorder? (3)
1) Parkinson’s
2) Tourette’s Syndrome
3) Huntington’s
1) Parkinson’s Disease
* cause?
disorder of motor system characterized by severe tremors & rigidity
- most common in elderly
- reduced activity of dopamine-secreting cells caused by cell death in substantia nigra
2) Tourette’s Syndrome
- characterized by?
- cause?
- treatment?
disorder characterized by various motor tics, involuntary vocalizations & odd, involuntary movement of body (face/head)
- caused by dysfunction in thalamus, basal ganglia & frontal cortex
- treated by reducing dopamine
3) Huntington’s Disease
* cause?
neurodegenerative genetic disorder that affects muscle coordination & leads to mental decline & behavioral symptoms
-
input pathways affected
- caudate & putamen
-
movement release
- erratic, uncontrolled
Forebrain > Limbic System
- location
- general function
- principal structures (3)
between neocortex & brainstem
- involved in emotion & memory processing
- role in rewarding properties of psychoactive drugs
composed of:
a) Amygdala
b) Hippocampus
c) Cingulate Cortex
Forebrain > Limbic System
a) Amygdala
- paired structure at base of caudate nucleus
- evaluates significance of info received
-
emotion processing
- recognition of emotion in others
Forebrain > Limbic System
a) Amygdala
- damage?
- activity
damage to amygdala results in tame behavior in situations that would otherwise evoke fear/stress
-
increased activity in people with depression/anxiety
*
Forebrain > Limbic System
b) Hippocampus
- location
- function
paired horseshoe-shaped structure forming lower part of border
- involved in:
- memory → semantic (facts/places)
- spatial navigation (directions
-
turning OFF stress response
- recieves info on stress hormone levels
- site of neurogenesis
Forebrain > Limbic System
c) Cingulate Cortex
above corpus callosum
- cognitive & emotional processing
- similar functions as prefrontal cortex
- active in attention, planning, decision-making, motivational states
Forebrain > Neocortex
- location
- function
- composed of? (4)
- outermost layer
- creates & responds to perceptual world
- sophisticated processing
4 lobes:
a) Occipital
b) Parietal
c) Temporal
d) Frontal
Forebrain > Neocortex
a) Occipital
- location
- function
Posterior part of brain
- visual functions (initial perception)
primary visual cortex - recieves info from thalamus & sends to other associated (extrastriate) regions for further processing
- tuned for color, movement, lines/orientation, shapes
Forebrain > Neocortex
a) Occipital
* damage
deficits in processing visual info
i.e. unable to identify shape/color of objects
Forebrain > Neocortex
b) Parietal
- location
- functions (3)
- regions
anterior to occipital lobe & above temporal lobe
Primary Somatosensory Cortex → tactile function (process info related to sense of touch) & sends to association cortices
- spatial processing (prioprioception)
- movement programming (directing towards goal/task)
- 2 point discrimination
Dorsal-Visual Stream
Forebrain > Neocortex
b) Parietal
* damage
difficulties identifying/locating stimulation on skin
Dorsal Visual Stream
“where” & “how” stream
pathway from primary visual cortex (V1) in occipital lobe into parietal lobe
- involved in spatial awareness & guiding actions
- info about body integrated with visual info
Forebrain > Neocortex
b) Parietal Lobe
- damage?
damage causes loss of movement coordination
Apraxia = motor programming impairment
- difficulty with motor planning to perform tasks
e. g., asked to use scissors → can’t show how to use, apply to wrong target, grab wrong part,
Split Brain Patients
severed corpus callosum used to treat severe epilepsy
- inhibits communication between hemispheres
- may experience alien-limb syndrome
- limb engages in movement without individual’s awareness/control over action
- image shown only in left VF → can’t say what they saw
- left VF → right hemisphere
- language processing → left hemisphere
Forebrain > Neocortex
c) Temporal Lobe
- location
- function
- important regions (2)
- involved in?
lateral side of brain below parietal & frontal lobe
- visual recognition (Ventral-Visual Stream)
- role in memory
- recognizing people (contains hippocampi)
Primary Auditory Cortex → auditory functions (music/language)
Wernicke’s Area
- Ventral-Visual Stream
Forebrain > Neocortex
c) Temporal Lobe
* Ventral-Visual Stream
“what” stream
associated with object recognition & representation & long-term memory storage
Forebrain > Neocortex
c) Temporal Lobe
* Wernicke’s Area
posterior part of temporal lobe
- involved in:
- production of written & spoken language
- language comprehension
Forebrain > Neocortex
c) Temporal Lobe
- Wernicke’s Area
- damage?
Aphasia
- fluent → connect words but lack meaning
- lack of comprehension (difficulty recognizing words)
Forebrain > Neocortex
c) Temporal Lobe
* damage?
Agnosia
- inability to recognize objects/faces/sounds
Forebrain > Neocortex
d) Frontal Lobe
anterior lobe
- ensures behavior is context-appropriate (Prefrontal Cortex)
- performs executive functions
-
programming movement
- precise (aided by basal ganglia & cerebellum)
Primary Motor Cortex
Broca’s Area
Forebrain > Neocortex
d) Frontal Lobe
* Broca’s area
motor aspect of language
- speech production
- involved in writing words
Forebrain > Neocortex
d) Frontal Lobe
- Broca’s area
- damage
non-fluent aphasia
- meaningful words but broken/stuttered speech
Forebrain > Neocortex
d) Frontal Lobe
* damage
difficulties organizing ongoing behavior & planning for future
Cytoarchectonics
- significance?
microscopic study of body tissue’s cellular composition
- used to make cortical maps based on cell organization, structure & distribution
Brodmann’s maps
differentiated cortical areas using cell characteristics
How else is the cortex mapped? (2)
- fMRI (functional MRI)
- brain stimulation
(10 Principles of NS function
1) NS creates movement & perception
2) Forever Changing (Plasticity)
3) Many Brain Circuits are Crossed
4) CNS has multiple levels of function
5) Brain is Symmetrical & Asymmetrical
6) Hierarchical & Parallel Organization
7) Sensory & Motor Divisions
8) Sensory input divided for object recognition & motor control
9) Localized & Distributed Functions
10) Uses Excitation & Inhibition
1) NS creates movement & perception
NS creates perceptual reality & allows us to act within it
2) Forever Changing (Plasticity)
brain is physically changed by experience
- plasticity = brain’s ability to change
3) Many Brain Circuits are Crossed
most sensory & motor inputs to/from brain are contralateral
4) CNS has multiple levels of function
sensory & motor processing occurs at many levels of CNS (spinal cord, brainstem & forebrain)
- higher levels allow for more elaborate processing
5) Brain is Symmetrical & Asymmetrical
Structural
- symmetry - primary sensory/motor cortices
- asymmetry - Wernicke’s area (larger in left H)
Functional
- symmetry - sensory & motor control
- asymmetry - language (left/Wernicke’s) vs music (right except musicians)
6) Hierarchical & Parallel Organization
hierarchical systems process info in series of steps with increasing complexity
parallel system processes info concurrently
- same info processed dif places & ways
7) Sensory & Motor Divisions
Peripheral NS
- spinal & cranial nerves = mixed
Central NS
- spinal cord to cortex
8) Sensory input divided for object recognition & motor control
sensory info used for:
- motor control (dorsal visual stream)
- object recognition (ventral visual stream)
these processes take place in parallel but distinct regions
9) Localized & Distributed Functions
basic functions are localized (controlled by specific brain region)
complex functions are distributed (multiple localized areas play role in function)
10) Uses Excitation & Inhibition
Parasympathetic vs. Sympathetic