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Anticancer > Microtubule Inhibitors > Flashcards

Microtubule Inhibitors Flashcards

1
Q

Microtubules inhibitors
Vinca alkaloids
Taxanes

A

Vinca Alkaloids

Vincristine
Vinblastine
Vinorelbine

Taxanes
Paclitaxel
Docetaxel
Cabazitaxel

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2
Q

Vinca alkaloids mechanisim

M phase

A

Binds to B tubulin subunits & inhibits polymerization of tubulin to Microtubules

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3
Q

Taxanes mech

M phase

A

Binds to specific site at B subunits . Inhibits proper polymerazation. Large unstable dysfunctional microtubules formed.

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Anticancer (7 decks)

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