Anti Tumor antibiotics Flashcards

1
Q

Anthracyclines

A

Doxorubicin
Daunorubicin
Idarubicin
Epirubicin

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2
Q

Anthracyclines mechanism

A

Damages DNA by intercalating b/w base pairs resulting in uncoiling of helix, inhibiting DNA synthesis

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3
Q

Glycopeptide antibiotic

A

Bleomycin

Binds to guanosine cytosine rich portions of DNA via S tripeptide & partial intercalation of the bithiazole rings

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