Anti Tumor antibiotics Flashcards
1
Q
Anthracyclines
A
Doxorubicin
Daunorubicin
Idarubicin
Epirubicin
2
Q
Anthracyclines mechanism
A
Damages DNA by intercalating b/w base pairs resulting in uncoiling of helix, inhibiting DNA synthesis
3
Q
Glycopeptide antibiotic
A
Bleomycin
Binds to guanosine cytosine rich portions of DNA via S tripeptide & partial intercalation of the bithiazole rings