Microscopic polyangitis Flashcards
1
Q
What is the definition of microscopic polyangitis?
A
A lower respiratory tract - renal syndrome without the involvement of the upper respiratory tract
2
Q
What age does microscopic polyangitis present?
A
64 - 72 years
3
Q
How do patients normally present with microscopic polyangitis?
A
- Pulmonary hemorrhage
- rapidly glomerularnephritis
- Prodrome : fever, malaise, athralgia
- Rash - palpable purpura
4
Q
Which antibody is found positive?
A
pANCA
5
Q
What are the results from blood tests?
A
- elevated ESR
- elevated CRP
- anaemia
6
Q
What features of renal impairment may be seen?
A
- high creatinine
- haematuria
- proteinuria
7
Q
What is the gold standard investigation?
A
- Kidney and lung biopsies
2. Kidneys show focal/segmental glomerularnephritis with epithelial crescent cells
8
Q
How is microscopic polyangitis different from Churg-Strauss/Wegener’s?
A
No granulomas present
