ANCA

Question 1

What are two types of ANCA?

Answer 1

1. Cytoplasmic ANCA

2. Perinuclear ANCA

Question 2

Name two conditions cANCA may be positive in?

Answer 2

1. Wenger’s granulomatosis
   (>90%)
2. Microscopic polyangitis (40%)

Question 3

Name 3 conditions pANCA may be positive in?

Answer 3

1. Microscopic polyangitis (75%)
2. Churg - Strauss syndrome
3. Primary sclerosing cholangitis

Question 4

Link between ANCA vs disease acitivity?

Answer 4

1. Correlation between cANCA and disease acitvity

2. No correlation between pANCA and disease acitvity.