microscopic polyangiitis Flashcards
1
Q
which vessels
A
small
2
Q
who gets
A
anyone
3
Q
causes?
A
autoimmune process that releases p-ANCA. binding to neutrophil causes a degranulation and constitutional symptoms. the enzymes targeted by the ANCAs are myeloperoxidase and proteinase 3
4
Q
treat
A
prednisone and cyclophosphamide
5
Q
symptoms
A
fever, anorexia, weight loss, fatigue, and renal failure, hematuria and proteinuria glomerulonephritis, palpable purpura, and splinter hemorrhages
6
Q
bare facts
A
small vessel, p-ANCA (MPO), necrotizing vasculitis caused by an autoimmune process that releases the antibodies. cases constitutional symptoms, renal failure, skin lesions, lung involvement and eye symptoms
