Microscopic Examination Flashcards
Polarized Light
2 things
Maltese cross pattern: cholesterol, starch, 4 glowing orbs in a clover pattern
Birefringent: glowing, most crystals, fibers, radiographic dye
Cells: Red Cells
causes, where, test result
Damage to vascular system, renal disease
RBC cast and proteinuria: kidney/upper UT
No RBC cast or proteinuria: lower UT
Test: positive blood pad
Cells: White Blood Cells
3 types, appearance and test result
Leukocyturia: inflammation, disease, infection
Casts and proteins: upper/kidney
Trace protein, no casts: lower/bladder
Appearance and test result: cloudy, smelly, positive leukocyte esterase
Cells: SEC
Poor collection, normal
Cells: TEC
Increased in what
Normal: 0-2
Increased: UTI, urinary inflammation
Cells: RTE
significance
Tubular cells, collecting duct cells
Always significant: upper kidney infection, renal disease, sheets = tubular injury/death
Cells: Oval Fat Bodies
RTE with absorbed fats, glomerular dysfunction with renal cell death
- Refractive
- Polarized microscope
- Fat stain
Casts: Basics and Formation
increased in what, disintegration?, significance
Formed in tubules, formation of Tamm-Horsfall protein
Increased: acidic, more solutes, stasis, more proteins
Disintegration: alkaline, dilute
Significance: more in number type and size
Casts: Homogenous - Hyaline
increased
Low refractile
Pretty normal
Increased: dehydration, exercise
Casts: Homogenous - Waxy
significance
NOT NORMAL
Highly refractile
Significance: chronic renal disease, renail failure, advanced stage cast
Casts: Inclusion - Granular
significance
Protein/cell degradation products, very refractile
NOT NORMAL (or heavy exercise)
Significance: renal disease
Casts: Inclusion - Fatty
signif.
Free fat or OFB, maltese cross pattern
NOT NORMAL
Significance: some renal diseases
Casts: Inclusion - Other
Elements: hemosiderin, crystals
Pigmented: hyaline with colo from myoglobin, hemoglobin, etc.
Casts: Cellular - RBC
NOT NORMAL
Significance: glomerular disease
Casts: Cellular - WBC
NOT NORMAL
Significance: glomerular disease, infection/inflammation