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PH 108 - Physical Pharmacy (Lec) > Micromeritics > Flashcards

Micromeritics Flashcards

1
Q

Science and technology of small particles

A

Micromeritics

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2
Q

Any unit of matter having defined physical dimensions

A

Particle

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3
Q

Expressed in diameter

A

Particle size

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4
Q

An estimate of the size range present and the number or weight fraction of each particle size

A

Particle size distribution

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5
Q

For particles > 1 μm; use calibrated stage and ocular micrometers

A

Optical microscopy

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6
Q

Measurement of the distance between tangents parallel to some fixed direction

A

Feret diameter

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7
Q

Diameter of a circle with the same area as that of the particle observed perpendicular to the surface on which the particle rests

A

Projected area diameter

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8
Q

Taken as the length of a line that bisects a particle

A

Martin diameter

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9
Q

Method of choice for classification of the coarser grades of single powders or granules

A

Sieving

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10
Q

Special cylindrical container designed such that a sample can be removed from the lower portion at selected time intervals

A

Adreasen apparatus

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11
Q

Coulter counter (Principle involved)

A

Electronic resistance

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12
Q

HIAV/Royco Light Blockage Instrument (Principle involved)

A

Light blockage

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13
Q

Beckman Coulter Model (Principle involved)

A

Photon correlation spectroscopy

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14
Q

Micro-computerized Mercury Porosimetry (Principle involved)

A

Adsorption

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15
Q

German Counter (Principle involved)

A

Faraday-Tyndall effect (Light scattering)

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16
Q

Measure of the total voids present in a particle

A

Porosity

17
Q

Closest or rhombohedral (Theoretical porosity)

A

26%

18
Q

Most open, loosest, or cubic packing (Theoretical porisity)

A

48%

19
Q

Ordinary powders (Theoretical porosity)

A

30-50%

20
Q

Flocculated powders (Theoretical porosity)

A

> 48%

21
Q

Crystalline materials (Theoretical porisity)

A

<1%

22
Q

Density exclusive of the voids and intraparticle pores larger than molecular or atomic dimensions in the crystal lattices

A

True density

23
Q

Density determined by the displacement of Hg

A

Granule density

24
Q

Measure of interparticulate interactions

A

Bulk density

25
Q

Achieved by mechanically tapping a measuring cylinder containing a powder sample

A

Tapped density

26
Q

Refers to specific bulk volume; reciprocal of bulk density

A

Bulkiness

27
Q

Powder flow measurement related to interparticulate friction or resistance to movement between particles

A

Angle of repose

28
Q

Generally measured as the mass per time flowing from any of a number of types of containers

A

Flow through an orfice

29
Q

Very course particle (Sieve no.)

A

8

30
Q

Coarse particle (Sieve no.)

A

20

31
Q

Moderately course (Sieve no.)

A

40

32
Q

Fine particle (Sieve no.)

A

60

33
Q

Very fine particle (Sieve no.)

A

80

PH 108 - Physical Pharmacy (Lec) (8 decks)

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