Microhematuria - LaGrange Flashcards
Definition of Asymptomatic Microhematuria
No symptoms, greater than 3 RBCs per high power field on microscopy. Urine dipstick positive for heme no adequate (must have 3 negative micros for one positive dipstick)
Risk factors for urologic malignancy (10)
1) Smoking
2) Males (BPH, prostate cancer prevalent)
3) Age >35
4) Occupational exposures (benzene, aromatic amines)
5) Analgesic abuse (phenacetin)
6) H/o gross hematuria
7) Hx pelvic radiation
8) Hx of chronic UTI
9) Hx alkylating chemo
10) Hx of chronic indwelling foreign body
How many positive micro UA is sufficient for workup
1
Top 3 causes of benign causes of AMH
BPH, UTI, Stones. Others: Obstructions, medical renal disease, benign tumors.
Standard imaging for microhematuria
Multiphasic CT without and with IV contrast
A) Non contrast: stones, hydronephrosis, fat lesions
B) Arterial phase: Tumors, inflammatory lesions
C) Venous stage: Scarring
D) Excretory phase: pyelogram, ureters, bladder
Cant have a CT with contrast (Pregnant, Contrast allergy, renal insufficiency) what do you do?
1) MRI/MRU without and with gadolinium contrast: Not as good for stones, better for masses. Not good in renal insufficiency
2) Retrograde pyelography: Safe with renal insufficiency. Plus Ultrasound.
-Must need some contrast to see inside kidney
What is the best way to rule out bladder cancer?
Cystoscopy- May miss many many bladder tumors depending on how full bladder is.
Recommendation for cystoscopy
All patients over 35 or younger than 35 with risk factors