Incontinence - Bishay Flashcards
Domains for defining continence (4)
Symptoms: patient/caregiver description
Signs: objective demonstration of urine loss
UDS observation
Condition: lower urinary tract pathophysiology
What is the involuntary loss of urine and is not necessarily a part of aging?
Incontinence
The micturation control center in your frontal cortex does what?
Inhibitory signals to the detrusor.
The pontine micturation center does what?
Coordinates Urinary Sphincter with detrusor
The spinal cord had what role in micturation?
Communication between brainstem and sacral spinal cord. Sacral spinal cord is spinal reflex center.
Classes of incontinence
Transient- Important in elderly Urge- Variant overactive bladder syndrome Stress- Leak with coughing Mixed: Stress and urge Total/continuous: rare Overflow: neurogenic baldder
Functional Classification of incontinence
1) Failure to empty (Bladder underactivity, obstruction)
2) Failure to store: (urethral incompetence, bladder overactivity)
Urologist Referral for Incontinence
- Bothersome Stress Incontinence
- Refractory Urge/Urge Incontinence
- Recurrent symptomatic UTI’s with urinary incontinence
- Pelvic floor prolapse
- Prostate cancer
- Bladder cancer
- Hematuria
- Urinary retention not responding to management
Urethral sphincter Etiology: Urethral resistance- When will you see leakage of urine?
During filling of bladder with valsalva
Results for post void residuals
400 consider intermittent catheterization or indwelling foley catheter and further urologic consult
Testing for incontinence
Labs: UA with possible culture
Urodynamics testing: Stress testing, uroflow, postvoid residual, voiding cystometrogram, cystourethroscopy
How should you begin therapy for incontinence?
- Begin with conservative therapy (Lifestyle changes- avoid caffeine, alcohol, etc.)
- Bladder diary
- Behavioral training: Timed, double voiding
Pharmaceutical therapy for incontinence
1) Anticholinergic Agent- Promote urinary storage by blocking Mu receptor. SE: Dry mouth, constipation
2) Beta 3 agonists- Mirabegron (Myrbetriq): Stimulates bladder relaxation promoting storage. SE: Occasional HTN
3) Tricyclic antidepressants (Imipramine)- consider for mixed incontinence
4) Estrogen: Elderly
Treatment modalities for incontinence- Surgery for Overactive bladder:
1) Catheter (intermittent, indwelling)
2) Surgery: Neuromodulation, Botulinum toxin, augmentation cytoplasty, denervation
Surgery for Stress Incontinence
1) Retropubic suspensions
2) Mid-urethral sling
3) Pelvic organ prolapse repair
4) Collaen injections
5) Artificial urinary sphincter