Microbiology - Shillitoe - Bacterial Infections of the Skin Flashcards

1
Q

Smears from pus may show gram + cocci in clumps or chains;
very contagious;
children common

A

Impetigo
usually a combination of S. aureus and S. pyogenes;
surface only (epidermis)

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2
Q
gram + cocci
coagulase +
beta-hemoytic
DNAase +
salt resistant
A

Staph aureus

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3
Q
gram +
coagulase -
beta hemolytic,
bacitracin sensitive
reactive with Strep Group A antiserum
A

Strep pyogenes

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4
Q

Bullous pemphigoid is associated with what bacteria due to the exfoliatoxin?

A

Staph aureus

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5
Q

Dissemination of impetigo

A

Fomites, contact

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6
Q

What are the virulence factors for Staph aureus?

A
SO MANY
Structural
--Protein A
--Capsule
--Coagulase
Toxins
--TSS toxin
--exfoliatoxin
--enterotoxin
--leukocidin
--DNAase
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7
Q

Biofilm protects organisms from the immune system;

piercings, medical devices

A

Staph epidermidis

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8
Q
gram +
cocci
growing in clumps
catalase +
coagulase -
non-hemolytic
A

Staph epidermidis

loves plastic and nylon

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9
Q

Severe itching due to cell-mediated hypersensitivity;
linear lesions;
wrists or genitals common

A

Scabies
Sarcoptes scabei
burrowing mite

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10
Q

Treatment for scabies

A

Permethrin to kill mite;

topical steroids for itching

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11
Q

What is furunculitis?

A

Superficial sweat gland or follicle infections, looks like acne
usually due to Staph aurues

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12
Q

What is a carbuncle?

A

Multiple skin abscesses fused sub-cutaneously

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13
Q

What anaerobic bacterium is commonly present along with Staph aureus in acne?

A

Propionobacterium acnes

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14
Q

How to treat abscesses

A

drain;
mupirocin ointment for mild cases;
Nafcillin or oxacillin for severe/systemic cases

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15
Q

What is scalded skin syndrome?

A

Widespread exfoliation due to a localized infection by S. Aureus;
often seen in newborns;
exfoliatoxin separates epidermal cells;
subcutaneous

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16
Q

TSS can be from which agents?

A

super-antigen toxic shock syndrome toxin (Staph aureus);
Streptococcal TSS toxin;
systemic immune reaction

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17
Q

deep infection of skin;

associated with fever, lymphadenopathy and bacteremia

A

cellulitis

erysipelas is more superficial;

S. pyogenes usually responsible, as with NF

18
Q

What makes Strep pyogenes the prime candidate for causing NF?

A

Potent protease enzyme

19
Q

NF can be caused by Step pyogenes or…

A

C. perfringens –> gas gangrene

20
Q

What is the treatment for cellulitis or erysipelas?

A

Pencillin or cephalosporin

21
Q

What complication is similar to rheumatic fever but tends to follow skin infections rather than Strep pharyngitis?

A

Post-streptococcal glomerulonephritis;
Associated with M protein strep types;
3-4 weeks later;
no treatment, recurrences can lead to kidney failure

22
Q

Enteric fever

Meningitis

A

S. typhimurium - Rose spots

N. meningitides - Petechial lesions

23
Q

Syphilis

A

T. pallidum Secondary stage rashes

24
Q

Typhus

A

Rickettsia - Hemorrhagic rash

25
Q

Measles

A

Measles virus - Macules

26
Q

Toxic shock syndrome

A

S. aureus - Desquamation

27
Q

Blastomycosis

A

B. dermatidis -Papules

28
Q

Bacterial endocarditis

A

Viridans Streptococci - Splinter hemorrhages

29
Q

Impetigo

A

Yellow crusted skin lesions – near nostrils typically - can spread across face and appear on trunk and limbs. More common in children. Very contagious. Some cases show severe bullae
(Bullous impetigo).

S. aureus and S. pyogenes

30
Q

Leprosy

A

M. leprae - surface infection

31
Q

Infected piercings / catheters

A

S. epidermidis - surface infection

32
Q

Scabies

A

Mites - surface infection

33
Q

Follicles/ sweat glands Abscess

A

S. aureus

34
Q

Erysipelas

A

S. pyogenes - subcutaneous infection

35
Q

Cellulitis

A

S. pyogenes

36
Q

Necrotizing fasciitis

A

S. pyogenes / others

37
Q

Surgical site / wound

infections

A

S. aureus / others

38
Q

coagulase-negative, beta hemolytic,

bacitracin-sensitive, reactive with Strep Group A antiserum

A

S. pyogenes

39
Q

Gram + cocci which are either coagulase-positive, beta hemolytic,
DNAse-positive, salt resistant

A

S aureus

40
Q

What toxin is associated with bollous impedigo?

A

Bullous impetigo is associated with S. aureus due to exfoliatin.