Microbiology of Respiratory Infections Flashcards

1
Q

What factor differentiates between harmless and virulent streptococci strains?

A

Alpha haemolytic and non haemolytic are often harmless. Beta haemolytic species are usually the ones that cause damage.

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2
Q

What strain of bordetella causes kennel cough?

A

Bronchoseptica

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3
Q

Describe bordetella bronchospetica

A

Strict aerobe gram negative rod

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4
Q

What other household species can bordetella bronchoseptica effect?

A

Cats

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5
Q

How effective is the kennel cough vaccine?

A

Not very, it only protects against one or two strains of the virus

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6
Q

Describe the pathogenic process of bordetella bronchoseptica

A

Adherence to the initial trauma of respiratory epithelium. Proliferation in the airways. Release of toxins causing irritation and coughing. Epithilial necrosis. Inflammation and interstitial pneumonia

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7
Q

Where is pasteurella multocida usually found?

A

In the oral cavity of dogs and other animals

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8
Q

Where does it commonly cause infection ?

A

secondary infection of upper respiratory tract and also in dog bite wound

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9
Q

What are the key features to identify pasteurella multocida?

A

Gram- negative rod, Oxidase positive, no growth on Mc-conkey

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10
Q

What is Rabbit ‘snuffles’?

A

P. Multocida infection of the upper respiratory tract

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11
Q

How does rabbit snuffles present?

A

Chronic nasal discharge and sneezing. Sometimes secondary skin disease on face due to being constantly moist

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12
Q

Where does p. multocida colonise in the rabbit?

A

Respiratory tract, middle ear, genitalia and occasionally lungs

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13
Q

If you see nodules in the lungs of rabbits but no URT symptoms what is the differential diagnosis excluding rabbit snuffles?

A

Uterine Adenoma carcinoma with metastatic spread

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14
Q

What B- haemolytic streptococci is highly virulent in the lungs?

A

s. zooepidemicus

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15
Q

How so streptococci respond to gram staining?

A

Gram positive

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16
Q

How does the M - protein contribute to stroptococcus pathogenicity ?

A

Halts the complement cascade and interferes with oppsonphagocytosis

17
Q

How does actinomyces viscous appear under gram staining ?

A

gram positive

18
Q

What disease does actinomyces viscosus cause in the dog?

A

granulomatous thoracic infection in dogs but also localised granulomatous abscesses of the skin

19
Q

What gram positive soil bacteria can also cause chronic suppurating thoracic granulomas?

A

Nocardia

20
Q

What pathology is associated with nocardiosis?

A

Copious red brown exudate in pleural cavity which may become chronic with adhesion formation.

21
Q

How does chlamydophilia felis present ?

A

Conjunctivitis with nasal discharge that progresses to interstitial bronchopneumonia in cats

22
Q

How does chlamydophilia felis reproduce?

A

Infect cells and builds reticulobodies which multiply by binary fission in fomites. They them shift back to elementary bodies and spread

23
Q

What stain can you use to visulise chlamydophilia felis?

A

Kosters stain

24
Q

What pathological findings are associated with Nasal aspergillosis?

A

Destruction of nasal turbinates, chronic granulomatous inflammation. Funghal hyphae

25
Q

What breed of dog seemed especially predisposed to nasal aspergillosis?

A

German shepards