Microbiology Of Perio

Question 1

what are the main perio pathogens

Answer 1

aggregatibacter actniomycetecomitans
p gingivalis
t forsythia

Question 2

what are the putative pair pathogens

Answer 2

p intermedia 
f nucleatum
p micros
e corrodes
t denitcola 
c rectus

Question 3

what are some uncultured organisms found

Answer 3

porhyromonas endodontalis
preveotella denticola
treponemes
PHYLUM

Question 4

what comes from the non sp plaque hypothesis

Answer 4

chronic gingivitis

Question 5

what comes form the sp plaque hypothesis

Answer 5

periodontiitn
red/organge couples
a actinomycetesomitans

Question 6

what is rapidly progressing periodontitis

Answer 6

keystone 97% - actinomycetecomitans

eikenlee corrodens

Question 7

what is the adhesion of AACTcomitans

Answer 7

fibrils
fimbriae
binds to ECM
capsule

Question 8

what is the toxin assc with AACTcomitans

Answer 8

leucotoxin kills PMNs and monocytes

Question 9

what are th other ways AACTcomitans have immunomodulation

Answer 9

induce B and T cells ( cell walls nd LPS)

cytokine induction - chaperonin

Question 10

what does LPS do

Answer 10

induces osteoclast prolif in vitro

Question 11

what does the capsular polysac do

Answer 11

stimulates osteoblast apoptosis

Question 12

what other factor affects tissue and bone destruction

Answer 12

collagenase

Question 13

where is LPS found

Answer 13

gm -ve cell wall

Question 14

what is ANUG assc with

Answer 14

f nucelatum
treponema vincentii

HIV
measles
malnutrition
HSV

Question 15

what does f nucelatum do

Answer 15

LPS
proteo enymes
synergistic action - form biofilms, tim p gingivalis = protease

Question 16

what are the risk factors linked with anug

Answer 16

absence of effective oH
gingivitis 10-21 days
smoking

Question 17

what is ecological plaque hypothesis

Answer 17

plaque inc = inflam response
comp and build GCF = GNABS
suppress host sp
MIX ACTIVE EFFECTS

Question 18

what is dysbiosis

Answer 18

disrupt in symbiotic survival

Question 19

what si the mechanisms of disease

Answer 19

fundamental idea that both the amount of virulence factors and inflam response response by the host are key contributors to disease process

Question 20

what is the perio treatement idea

Answer 20

mechanical - reduce bac load
systemic Ab
topical

Question 21

what is done in supra gingival plaque removal

Answer 21

effect even deep pocket
reduce inflam and GCF flow
nutrient flow from supra to sub - Gm +ve inc and peiropathogen dec

Question 22

does supra gingival plaque removal prevent LOA

Answer 22

no - not on tis own

Question 23

what si the use of Ab like

Answer 23

systemic
slim all pathogens
short/long term

Question 24

what is the long tern use of Ab for

Answer 24

aggressive- JP
periodontitis
prepubertal periodontitis

Question 25

whats the problems of using Ab

Answer 25

against biofilm
resistance
not evidence of mechanical debridement

Question 26

what resume Ab considered

Answer 26

metronidazole

tetracycline

Question 27

when metornidaxole used

Answer 27

in com with scale an polish not amazing effects
narrow spectrum
limited use for facultative capnphilic orgs

Question 28

what si combined with metronidazole

Answer 28

amoxicillin
control red and orange complex
AACTcomitans

Question 29

what does tetracycline do

Answer 29

reduce inflam and block collagenase

issue with resistance

Question 30

what are macrolides proposed to do

Answer 30

anti inflam

Question 31

what does ciprofloxacin do

Answer 31

inhibits AACTcomitans

oeniciclin allergy