Microbiology, Antibiotics, Inhibition of cell wall synthesis

Question 1

Meropenem

Answer 1

• inhibition of cell wall synthesis
• beta lactam
• affects most bacterium including anaerobes

Question 2

Benzylpenicillin

Answer 2

• inhibition of cell wall synthesis- beta lactam
• also called penicillin G
• affects G+ largely but also Neisseria Meningitidis (G-)
• best choice for Streptococcus Pneumoniae, Neisseria Meningitidis, Streptococcus Pyogenes

Question 3

Imipenem

Answer 3

• inhibition of cell wall synthesis
• beta lactam
• affects most bacterium including anaerobes

Question 4

Flucloxacillan

Answer 4

• inhibition of cell wall synthesis
• beta lactam
• affects Staphylococci (G+)
• first choice of treatment for Staphylococci

Question 5

Amoxicillian

Answer 5

• inhibition of cell wall synthesis
• beta lactam
• affects G- largely but also Streptococci, Enterococci (G+)
• better absorption than penicillin G
• 20%-30% coliforms resistant due to beta-lactamase production

Question 6

Pipperacillan

Answer 6

• inhibition of cell wall synthesis
• beta lactam
• affects G- largely (but broad spectrum)

Question 7

Co-amoxiclav

Answer 7

• inhibition of cell wall synthesis
• beta lactam
• affects G-
• extends to cover beta-lactamase producing coliforms

Question 8

Ampicillan

Answer 8

• inhibition of cell wall synthesis
• beta lactam
• affects G- largely but also Streptococci, Enterococci (G+)
• better absorption than penicillin G

Question 9

Cephalosporins

Answer 9

• inhibition of cell wall synthesis
• cephalosporins
• G+ and G-

Question 10

Teicoplanin

Answer 10

• inhibition of cell wall synthesis
• glycopeptides
• affects G+ only

Question 11

Vancomycin

Answer 11

• inhibition of cell wall synthesis
• glycopeptides
• affects G+ only