Microbiology, Antibiotics, All functions

Question 1

Pipperacillan

Answer 1

• inhibition of cell wall synthesis
• beta lactam
• affects G- largely (but broad spectrum)

Question 2

Cephalosporins

Answer 2

• inhibition of cell wall synthesis
• cephalosporins
• G+ and G-

Question 3

Imipenem

Answer 3

• inhibition of cell wall synthesis
• beta lactam
• affects most bacterium including anaerobes

Question 4

Quinolone

Answer 4

• inhibitor of nucleic acid synthesis
• quinolones
• affects G- and Staphylococcus and Streptococcus (G+)
• the only oral solution against pseudomonas

Question 5

Clindamycin

Answer 5

• inhibition of protein synthesis
• licosamide
• affects anaerobes and G+

Question 6

Erythromycin

Answer 6

• inhibition of protein synthesis
• tetracycline macrolide
• affects G+ and Chlamydia psittacci, Coxiella burnetti, Mycoplasma pneumoniae

Question 7

Daptomycin

Answer 7

• inhibition of protein synthesis
• cyclic lipopeptide
• affects G+ and MRSA

Question 8

Ampicillan

Answer 8

• inhibition of cell wall synthesis
• beta lactam
• affects G- largely but also Streptococci, Enterococci (G+)
• better absorption than penicillin G

Question 9

Linezolid

Answer 9

• inhibition of protein synthesis
• oxazolidinones
• affects MRSA

Question 10

Teicoplanin

Answer 10

• inhibition of cell wall synthesis
• glycopeptides
• affects G+ only

Question 11

Clarithromycin

Answer 11

• inhibition of protein synthesis
• tetracycline macrolide
• affects G+ and Chlamydia psittacci, Coxiella burnetti, Mycoplasma pneumoniae

Question 12

Gentamicin

Answer 12

• inhibition of protein synthesis
• aminoglycosides
• affects G- and staphylococci (G+)

Question 13

Amoxicillian

Answer 13

• inhibition of cell wall synthesis
• beta lactam
• affects G- largely but also Streptococci, Enterococci (G+)
• better absorption than penicillin G
• 20%-30% coliforms resistant due to beta-lactamase production

Question 14

Nitrofurantoin

Answer 14

• inhibits nucleic acid synthesis
• lower UTI
• G- (mostly)

Question 15

Ciproflaxacin

Answer 15

• inhibitor of nucleic acid synthesis
• fluroquinolones
• nearly all G- including pseudomonas
• no usage on children (interference with cartilage growth)

Question 16

Meropenem

Answer 16

• inhibition of cell wall synthesis
• beta lactam
• affects most bacterium including anaerobes

Question 17

Vancomycin

Answer 17

• inhibition of cell wall synthesis
• glycopeptides
• affects G+ only

Question 18

Co-amoxiclav

Answer 18

• inhibition of cell wall synthesis
• beta lactam
• affects G-
• extends to cover beta-lactamase producing coliforms

Question 19

Azithromycin

Answer 19

• inhibition of protein synthesis
• tetracycline macrolide
• affects Chlamydia

Question 20

Trimethoprim

Answer 20

• inhibitor of nucleic acid synthesis
• trimethoprim & sulphamethoxazole
• treats urinary infections (inhibits purine synthesis)

Question 21

Fusidic Acid

Answer 21

• inhibition of protein synthesis
• G+ (staphylococci)

Question 22

Levoflaxin

Answer 22

• inhibitor of nucleic acid synthesis
• newer quinolones
• affects Pneumococci, Chlamydia psittacci, Coxiella burnetti, Mycoplasma pneumonia (mostly pneumonia)

Question 23

Nalidixic acid

Answer 23

• inhibitor of nucleic acid synthesis
• quinolones
• G- aerobes (coliforms)

Question 24

Flucloxacillan

Answer 24

• inhibition of cell wall synthesis
• beta lactam
• affects Staphylococci (G+)
• first choice of treatment for Staphylococci

Question 25

Benzylpenicillin

Answer 25

• inhibition of cell wall synthesis- beta lactam
• also called penicillin G
• affects G+ largely but also Neisseria Meningitidis (G-)
• best choice for Streptococcus Pneumoniae, Neisseria Meningitidis, Streptococcus Pyogenes

Question 26

Tetracyclines

Answer 26

• inhibition of protein synthesis
• tetracycline macrolide
• broad spectrum